The objective of this study was to examine the effects of patellar resurfacing on patellofemoral joint contact pressure and contact area in total knee arthroplasty. We tested seven fresh-frozen cadaveric knees using a custom knee jig which permits the simulation of physiologic quadriceps loading. Before patellar resurfacing, the mean peak contact pressure of medial and lateral patellofemoral joints was less than 10 MPa at knee flexion angles of 30 degrees, 60 degrees and 90 degrees, that of medial and lateral patellofemoral joints were 11.63 MPa and 11.42 MPa at a knee flexion angle of 120 degrees respectively, and the mean contact area of patellofemoral joint ranged from 70 to 150 mm2. After patellar resurfacing, the mean peak contact pressure of medial and lateral patellofemoral joints ranged from 50 to 100 Mpa (P<0.05), which exceeds the yield strength of ultrahigh molecular weight polyethylene, and the mean contact area of patellofemoral joint reduced to 10-15 mm2 (P<0.05). The contact pressure of patellofemoral joint was lower than the yield strength of articular cartilage before patellar resurfacing. Our results indicate that the yield stress of UHMWPE is exceeded after patellar resurfacing.