Biomaterial Database

Clustering strategies on tasks of verbal fluency in Parkinson's disease. 1992

S A Raskin, and M Sliwinski, and J C Borod

Department of Rehabilitation Medicine, Mount Sinai Medical Center, New York, NY 10029.

The verbal output of patients with Parkinson's disease (PD) was analyzed for semantic and phonemic clusters on tasks of verbal fluency. One task required cued retrieval by semantic category (i.e. animals), and one required non-cued retrieval by initial letter (e.g. words beginning with 'F'). Nondemented PD patients (N = 25) produced significantly fewer words on the cued semantic retrieval task than age-, gender- and education-matched normal control subjects (N = 22), but were not impaired on the non-cued letter retrieval task. However, overall, PD patients were able to form more semantic clusters than phonemic clusters. These results are discussed in light of other studies of verbal fluency deficits in patients with PD.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009483	Neuropsychological Tests	Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.	Aphasia Tests,Cognitive Test,Cognitive Testing,Cognitive Tests,Memory for Designs Test,Neuropsychological Testing,AX-CPT,Behavioral Assessment of Dysexecutive Syndrome,CANTAB,Cambridge Neuropsychological Test Automated Battery,Clock Test,Cognitive Function Scanner,Continuous Performance Task,Controlled Oral Word Association Test,Delis-Kaplan Executive Function System,Developmental Neuropsychological Assessment,Hooper Visual Organization Test,NEPSY,Neuropsychologic Tests,Neuropsychological Test,Paced Auditory Serial Addition Test,Repeatable Battery for the Assessment of Neuropsychological Status,Rey-Osterrieth Complex Figure,Symbol Digit Modalities Test,Test of Everyday Attention,Test, Neuropsychological,Tests, Neuropsychological,Tower of London Test,Neuropsychologic Test,Test, Cognitive,Testing, Cognitive,Testing, Neuropsychological,Tests, Cognitive
D010300	Parkinson Disease	A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)	Idiopathic Parkinson Disease,Lewy Body Parkinson Disease,Paralysis Agitans,Primary Parkinsonism,Idiopathic Parkinson's Disease,Lewy Body Parkinson's Disease,Parkinson Disease, Idiopathic,Parkinson's Disease,Parkinson's Disease, Idiopathic,Parkinson's Disease, Lewy Body,Parkinsonism, Primary
D011939	Mental Recall	The process whereby a representation of past experience is elicited.	Recall, Mental
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D012660	Semantics	The relationships between symbols and their meanings.	Semantic
D014705	Verbal Behavior	Includes both producing and responding to words, either written or spoken.	Behavior, Verbal,Behaviors, Verbal,Verbal Behaviors