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Autoimmune T lymphocytes can be used under appropriate conditions to induce resistance to the specific autoimmune disease that they usually produce. This practice, termed T cell vaccination, was found to be effective with the injection of a low (subpathogenic) number of autoaggressive T line lymphocytes. We report here that T cell vaccination produced marked resistance to the expression of experimental autoimmune uveoretinitis (EAU) in Lewis rats. In addition, vaccination led to the appearance of lymphoid cells in the vaccinated rats that demonstrated proliferative responses against idiotypic and ergotypic specificities of the injected T cells. This is the first report demonstrating the effector T lymphocytes specific for ocular antigens may be used as agents to modulate immunopathogenic responses responsible for EAU.
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
April 1986,
Immunology,
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
August 1991,
Current eye research,
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
January 1987,
Japanese journal of ophthalmology,
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
April 1991,
Journal of autoimmunity,
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
February 1986,
Journal of immunology (Baltimore, Md. : 1950),
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
April 1998,
Investigative ophthalmology & visual science,
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
February 1997,
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
July 1988,
Experimental eye research,
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
February 1991,
Journal of autoimmunity,
E Beraud, and
S Kotake, and
R R Caspi, and
S M Oddo, and
C C Chan, and
I Gery, and
R B Nussenblatt
March 1988,
Investigative ophthalmology & visual science,
