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Infection of BALB/c mouse cells with UV-irradiated herpes simplex virus (HSV) types 1 and 2 resulted in activation of a xenotropic type C virus detected by infectious center formation in permissive rat cells. The levels of type C virus activated by HSV were related to the UV dose and the multiplicity of infection used. The ability of HSV to activate type C virus was eliminated by heat-inactivation and by neutralization with specific antiserum against HSV, but was not affected by purification or treatment with DNase and RNase. Maximum levels of type C virus in the cells and medium were observed within 1 day after HSV infection, and the levels returned to control cell values within 3-4 days. The possible significance of these findings with respect to the putative oncogenic potential of HSV is discussed.
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
August 1977,
The Journal of general virology,
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
February 1980,
The Journal of general virology,
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
February 1977,
Virology,
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
April 1982,
International journal of cancer,
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
May 1978,
The Journal of general virology,
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
October 1976,
Acta virologica,
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
March 1976,
Infection and immunity,
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
February 2007,
Emerging infectious diseases,
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
May 1980,
Virology,
B Hampar, and
S A Aaronson, and
J G Derge, and
M Chakrabarty, and
S D Showalter, and
C Y Dunn
March 2003,
Nihon rinsho. Japanese journal of clinical medicine,
