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15 kidney biopsies from 13 patients with a combination of membranous nephropathy and amyloidosis were studied. Membranous nephropathy is shown to precede the development of amyloidosis which possesses all the properties of the acquired one (AA-amyloid). Transformation of membranous nephropathy into amyloidosis is due to the deficiency of the immune system characteristic of both processes. This combination is not considered as a special type of amyloidosis but as a peculiar feature of membranous nephropathy.
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