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The glucose-6-phosphate dehydrogenase and transketolase activities in mitochondria and hyaloplasm of the rabbit liver were studied as affected by ACTH injected daily in a dose of 10 u/kg of weight for two weeks. It was shown that the activity of glucose-6-phosphate dehydrogenase was unchanged neither in mitochondria nor in hyaloplasm. The transketolase activity in hyaloplasm was not changed as well. But in mitochondria it decreases by 47% (by an increase of sedoheptulose-7-phosphate S-7-P) simultaneously the ribose-5-phosphate (R-5-P) conversion is inhibited by 35%. The ratio of converted R-5-P and formed S-7-P became 2:0.68 (instead of theoretical 2:1). Administration of ACTH has no effect on the total concentration of acid-soluble ribose-containing compounds in both mitochondria and hyaloplasm.
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
January 1970,
Endocrinologia experimentalis,
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
January 1971,
Ukrains'kyi biokhimichnyi zhurnal,
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
January 1974,
Problemy endokrinologii,
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
January 1973,
Voprosy meditsinskoi khimii,
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
January 1973,
Voprosy meditsinskoi khimii,
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
January 1972,
Ukrains'kyi biokhimichnyi zhurnal,
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
December 1976,
The Biochemical journal,
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
July 1961,
Bollettino della Societa italiana di biologia sperimentale,
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
January 1965,
Federation proceedings. Translation supplement; selected translations from medical-related science,
N M Gula, and
Y L Germanyuk, and
E M Myt'kova
July 1952,
Nature,
