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In this review we summarise the current state of knowledge of the therapeutic efficacy and mechanisms of action of CoQ(10) in cardiovascular disease. Our conclusions are: 1. There is promising evidence of a beneficial effect of CoQ(10) when given alone or in addition to standard therapies in hypertension and in heart failure, but less extensive evidence in ischemic heart disease. 2. Large scale multi-centre prospective randomised trials are indicated in all these areas but there are difficulties in funding such trials. 3. Presently, due to the notable absence of clinically significant side effects and likely therapeutic benefit, CoQ(10) can be considered a safe adjunct to standard therapies in cardiovascular disease.
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
July 2002,
The Journal of cardiovascular nursing,
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
December 2005,
Shock (Augusta, Ga.),
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
June 2021,
Antioxidants (Basel, Switzerland),
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
December 2023,
Current cardiology reports,
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
April 2020,
Antioxidants (Basel, Switzerland),
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
January 2023,
Current diabetes reviews,
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
February 2021,
Journal of the American College of Cardiology,
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
May 2021,
Nutrients,
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
May 2021,
Antioxidants (Basel, Switzerland),
Salvatore Pepe, and
Silvana F Marasco, and
Steven J Haas, and
Freya L Sheeran, and
Henry Krum, and
Franklin L Rosenfeldt
September 1995,
British dental journal,
