Biomaterial Database

Susceptibility of salmonid alphavirus to a range of chemical disinfectants. 2007

D A Graham, and K Cherry, and C J Wilson, and H M Rowley

Veterinary Sciences Division, Agri-Food Biosciences Institute of Northern Ireland (AFBINI), Stormont, Belfast, UK. david.graham@afbini.gov.uk

A range of commercially available disinfectants were tested for efficacy against salmonid alphavirus under a range of different conditions including variations in concentration, temperature, contact time, water type and presence or absence of organic matter. Testing was based on the protocol defined in the draft European Standard prEN 14675, for which the effective standard is a 4 log(10) reduction in viral titre. All disinfectants were found to be effective under at least some of the conditions tested. However, the presence of organic matter in particular was shown to be detrimental in some cases, either through rendering some disinfectants ineffective, or by production of a visible inhomogeneity.

UI	MeSH Term	Description	Entries
D010545	Peroxides	A group of compounds that contain a bivalent O-O group, i.e., the oxygen atoms are univalent. They can either be inorganic or organic in nature. Such compounds release atomic (nascent) oxygen readily. Thus they are strong oxidizing agents and fire hazards when in contact with combustible materials, especially under high-temperature conditions. The chief industrial uses of peroxides are as oxidizing agents, bleaching agents, and initiators of polymerization. (From Hawley's Condensed Chemical Dictionary, 11th ed)	Peroxide
D004202	Disinfectants	Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)	Biocide,Disinfectant,Biocides
D005393	Fish Diseases	Diseases of freshwater, marine, hatchery or aquarium fish. This term includes diseases of both teleosts (true fish) and elasmobranchs (sharks, rays and skates).	Disease, Fish,Diseases, Fish,Fish Disease
D000524	Alphavirus	A genus of TOGAVIRIDAE, also known as Group A arboviruses. They are serologically related to each other and are transmitted by mosquitoes. The type species is the SINDBIS VIRUS.	Arboviruses, Group A,Barmah forest virus,Getah virus,Sagiyama virus,Alpha Virus,Alphaviruses,Alpha Viruses,Arbovirus, Group A,Group A Arbovirus,Group A Arboviruses
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012487	Salmonidae	A family of anadromous fish comprising SALMON; TROUT; whitefish; and graylings. They are the most important food and game fishes. Their habitat is the northern Atlantic and Pacific, both marine and inland, and the Great Lakes. (Nelson: Fishes of the World, 1976, p97)	Graylings,Thymallus,Whitefish,Salmonids,Grayling,Salmonid
D013464	Sulfuric Acids	Inorganic and organic derivatives of sulfuric acid (H2SO4). The salts and esters of sulfuric acid are known as SULFATES and SULFURIC ACID ESTERS respectively.	Acids, Sulfuric
D017835	Nedocromil	A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including EOSINOPHILS; NEUTROPHILS; MACROPHAGES; MAST CELLS; MONOCYTES; AND PLATELETS.	9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid,Alocril,Brionil,Cetimil,FPL-59002,Halamid,Irtan,Nedocromil Calcium,Nedocromil Sodium,Nedocromil, Calcium Salt (1:1),Nedocromil, Disodium Salt,Nedocromil, Disodium salt, Hydrate,Rapitil,Tilad,Tilade,Tilaire,Tilavist,Calcium, Nedocromil,FPL 59002,FPL59002,Sodium, Nedocromil
D018354	Alphavirus Infections	Virus diseases caused by members of the ALPHAVIRUS genus of the family TOGAVIRIDAE.	Getah Virus Infection,Sagiyama Virus Infection,Semliki Forest Virus Infection,Sindbis Fever,Sindbis Virus Infection,Alpha Virus Infections,Barmah Forest Virus Infection,Infections, Alphavirus,Mayaro Virus Infection,O'nyong-nyong Virus Infection,Alpha Virus Infection,Alphavirus Infection,Fever, Sindbis,Infection, Alphavirus,Infection, Getah Virus,Infection, Mayaro Virus,Infection, O'nyong-nyong Virus,Infection, Sagiyama Virus,Infection, Sindbis Virus,O'nyong nyong Virus Infection,O'nyong-nyong Virus Infections,Sindbis Fevers,Sindbis Virus Infections,Virus Infection, Alpha,Virus Infection, Getah,Virus Infection, Mayaro,Virus Infection, O'nyong-nyong,Virus Infection, Sagiyama,Virus Infection, Sindbis
D023382	Toxicity Tests, Acute	Experiments designed to determine the potential toxic effects of one-time, short-term exposure to a chemical or chemicals.	Acute Toxicity Tests,Acute Toxicity Test,Test, Acute Toxicity,Tests, Acute Toxicity,Toxicity Test, Acute