Comparing methods of quantifying diplopia. 2007

Sarah R Hatt, and David A Leske, and Jonathan M Holmes
Department of Ophthalmology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

OBJECTIVE Quantification of diplopia is important for describing severity of strabismus, measuring change over time, and reporting surgical outcomes. The cervical range of motion (CROM) method has been proposed as a simple, inexpensive alternative to the Goldmann perimeter for quantifying diplopia. The purpose of this study was to compare these 2 techniques and describe advantages and disadvantages. METHODS Cohort study. METHODS Seventy-six consecutive patients with binocular diplopia associated with any type of strabismus. METHODS Patients underwent diplopia assessment with the CROM method and Goldmann perimeter; diplopia was scored between 0 and 100 based on previously published scoring systems. Where CROM and Goldmann results were disparate by >20 points, the medical record was reviewed independently by 2 clinicians to determine the most likely reason for the discrepancy. METHODS (1) Measure of agreement between diplopia scores using the CROM and Goldmann methods using the kappa test and (2) the reasons for any disagreement between tests of >20 points. RESULTS Overall agreement between the 2 tests was good (intraclass correlation coefficient, 0.65; 95% confidence interval, 0.50-0.77). In 49 (64%) of 76 tests, the CROM and Goldmann results were within 20 points. Of the 27 (36%) showing a more than 20-point discrepancy, 17 were worse using the Goldmann technique and 10 were worse using the CROM technique. The most frequent reason for worse diplopia using the Goldmann technique was poorer ability to fuse or suppress in the Goldmann apparatus compared with the real-world targets used in free space for the CROM method. Worse diplopia using the CROM method most often was the result of the deviation being present for distance only. In some cases, differences were the result of the greater weighting of primary position using the current scoring system for the CROM method. CONCLUSIONS In most cases, the CROM and Goldmann methods provide equivalent measures of diplopia severity. However, the Goldmann method seems to overestimate diplopia in patients with fragile fusion or tenuous suppression and seems to underestimate diplopia in deviations present for distance only. The CROM method may be more representative of diplopia severity as experienced in everyday life.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004172 Diplopia A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE. Double Vision,Polyopsia,Diplopia, Cortical,Diplopia, Horizontal,Diplopia, Intermittent,Diplopia, Monocular,Diplopia, Refractive,Diplopia, Unilateral,Diplopia, Vertical,Cortical Diplopia,Cortical Diplopias,Diplopias,Diplopias, Cortical,Diplopias, Horizontal,Diplopias, Intermittent,Diplopias, Monocular,Diplopias, Refractive,Diplopias, Unilateral,Diplopias, Vertical,Horizontal Diplopia,Horizontal Diplopias,Intermittent Diplopia,Intermittent Diplopias,Monocular Diplopia,Monocular Diplopias,Polyopsias,Refractive Diplopia,Refractive Diplopias,Unilateral Diplopia,Unilateral Diplopias,Vertical Diplopia,Vertical Diplopias,Vision, Double
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old

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