| D007968 |
Leukoencephalopathy, Progressive Multifocal |
An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7) |
Encephalitis, JC Polyomavirus,Progressive Multifocal Leukoencephalopathy,JC Polyomavirus Encephalopathy,Encephalopathies, JC Polyomavirus,Encephalopathy, JC Polyomavirus,JC Polyomavirus Encephalitis,Leukoencephalopathies, Progressive Multifocal,Multifocal Leukoencephalopathies, Progressive,Multifocal Leukoencephalopathy, Progressive,Progressive Multifocal Leukoencephalopathies |
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| D008297 |
Male |
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Males |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D000369 |
Aged, 80 and over |
Persons 80 years of age and older. |
Oldest Old |
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| D012514 |
Sarcoma, Kaposi |
A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause. |
Kaposi Sarcoma,Kaposi's Sarcoma,Multiple Idiopathic Pigmented Hemangiosarcoma,Kaposis Sarcoma,Sarcoma, Kaposi's |
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| D012878 |
Skin Neoplasms |
Tumors or cancer of the SKIN. |
Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm |
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| D017809 |
Fatal Outcome |
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept. |
Fatal Outcomes,Outcome, Fatal,Outcomes, Fatal |
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| D018344 |
T-Lymphocytopenia, Idiopathic CD4-Positive |
Reproducible depletion of CD4+ lymphocytes below 300 per cubic millimeter in the absence of HIV infection or other known causes of immunodeficiency. This is a rare, heterogeneous syndrome and does not appear to be caused by a transmissible agent. |
CD4-Positive T-Lymphocytopenia, Idiopathic,Idiopathic CD4-Positive T-Lymphocytopenia,CD4+ T-Lymphocytopenia,CD4+ T-Lymphocytopenia, Idiopathic,Idiopathic CD4 Positive T-Lymphocytopenia,Idiopathic CD4+ T-Lymphocytopenia,T-Lymphocytopenia, Idiopathic CD4+,CD4 Positive T Lymphocytopenia, Idiopathic,CD4+ T Lymphocytopenia,CD4+ T Lymphocytopenia, Idiopathic,CD4+ T-Lymphocytopenias,Idiopathic CD4+ T Lymphocytopenia,T Lymphocytopenia, Idiopathic CD4 Positive,T Lymphocytopenia, Idiopathic CD4+,T-Lymphocytopenia, CD4+,T-Lymphocytopenias, CD4+ |
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