Auditory cortical activation and speech perception in cochlear implant users. 2008

K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
Department of Otolaryngology, Manchester Royal Infirmary Manchester, UK. kmjgreen@rcsed.ac.uk

Cochlear implantation is generally accepted as a successful means of restoring auditory sensation to profoundly deaf individuals. Although most patients can expect a satisfactory outcome following implantation, some have poor speech perception outcomes. This investigation used [18F]-fluorodeoxyglucose positron emission tomography to measure cortical activity resulting from auditory stimulation in seven 'good' and four 'poor' cochlear implant recipients. Activations were significantly greater in both the primary and association cortices in the good compared with the poor implant users. We suggest that the ability to access the more specialised speech processing abilities of the auditory association cortices helps determine outcome following cochlear implantation.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D003054 Cochlear Implants Electronic hearing devices typically used for patients with normal outer and middle ear function, but defective inner ear function. In the COCHLEA, the hair cells (HAIR CELLS, VESTIBULAR) may be absent or damaged but there are residual nerve fibers. The device electrically stimulates the COCHLEAR NERVE to create sound sensation. Auditory Prosthesis,Cochlear Prosthesis,Implants, Cochlear,Auditory Prostheses,Cochlear Implant,Cochlear Prostheses,Implant, Cochlear,Prostheses, Auditory,Prostheses, Cochlear,Prosthesis, Auditory,Prosthesis, Cochlear
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D001303 Auditory Cortex The region of the cerebral cortex that receives the auditory radiation from the MEDIAL GENICULATE BODY. Brodmann Area 41,Brodmann Area 42,Brodmann's Area 41,Heschl Gyrus,Heschl's Gyrus,Auditory Area,Heschl's Convolutions,Heschl's Gyri,Primary Auditory Cortex,Temporal Auditory Area,Transverse Temporal Gyri,Area 41, Brodmann,Area 41, Brodmann's,Area 42, Brodmann,Area, Auditory,Area, Temporal Auditory,Auditory Areas,Auditory Cortex, Primary,Brodmanns Area 41,Cortex, Auditory,Cortex, Primary Auditory,Gyrus, Heschl,Gyrus, Heschl's,Gyrus, Transverse Temporal,Heschl Convolutions,Heschl Gyri,Heschls Convolutions,Heschls Gyri,Heschls Gyrus,Primary Auditory Cortices,Temporal Auditory Areas,Temporal Gyrus, Transverse,Transverse Temporal Gyrus
D013067 Speech Perception The process whereby an utterance is decoded into a representation in terms of linguistic units (sequences of phonetic segments which combine to form lexical and grammatical morphemes). Speech Discrimination,Discrimination, Speech,Perception, Speech
D016896 Treatment Outcome Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series. Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D049268 Positron-Emission Tomography An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower. PET Imaging,PET Scan,Positron-Emission Tomography Imaging,Tomography, Positron-Emission,Imaging, PET,Imaging, Positron-Emission Tomography,PET Imagings,PET Scans,Positron Emission Tomography,Positron Emission Tomography Imaging,Positron-Emission Tomography Imagings,Scan, PET,Tomography Imaging, Positron-Emission,Tomography, Positron Emission

Related Publications

K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
September 2012, International journal of pediatric otorhinolaryngology,
K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
January 2000, Advances in oto-rhino-laryngology,
K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
June 2005, Cochlear implants international,
K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
January 2022, PloS one,
K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
December 2002, The Laryngoscope,
K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
September 1986, The American journal of otology,
K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
February 2020, Current opinion in neurobiology,
K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
May 2000, Hearing research,
K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
June 2005, Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
K M J Green, and P J Julyan, and D L Hastings, and R T Ramsden
February 2012, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
Copied contents to your clipboard!