Polyelectrolytes at the endothelial cell surface. 1991

A Silberberg
Department of Polymer Research, Weizmann Institute of Science, Rehovot, Israel.

It is recalled that the tension in a stretched polyelectrolyte chain mechanically compensates both the coulomb interaction and the hydrostatic pressure increase around the chain in a compromise which minimises the free energy and keeps water chemical potential constant throughout. Stretching strongly favors parallel cylinder nematic order in polyelectrolyte brushes on a surface or in the slit between two surfaces when the polyelectrolyte chains function as bridges. Strong, stiffly stretched chains result when the molarity of the fixed charge distribution is larger than the molarity of the neutral salt solution with which the brushes are in equilibrium. The relevance of these two systems to the endothelial cells which cover the walls of blood vessels is discussed.

UI MeSH Term Description Entries
D008562 Membrane Glycoproteins Glycoproteins found on the membrane or surface of cells. Cell Surface Glycoproteins,Surface Glycoproteins,Cell Surface Glycoprotein,Membrane Glycoprotein,Surface Glycoprotein,Glycoprotein, Cell Surface,Glycoprotein, Membrane,Glycoprotein, Surface,Glycoproteins, Cell Surface,Glycoproteins, Membrane,Glycoproteins, Surface,Surface Glycoprotein, Cell,Surface Glycoproteins, Cell
D002462 Cell Membrane The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells. Plasma Membrane,Cytoplasmic Membrane,Cell Membranes,Cytoplasmic Membranes,Membrane, Cell,Membrane, Cytoplasmic,Membrane, Plasma,Membranes, Cell,Membranes, Cytoplasmic,Membranes, Plasma,Plasma Membranes
D004573 Electrolytes Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed) Electrolyte
D004730 Endothelium, Vascular Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components. Capillary Endothelium,Vascular Endothelium,Capillary Endotheliums,Endothelium, Capillary,Endotheliums, Capillary,Endotheliums, Vascular,Vascular Endotheliums

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