[Cisplatin, adriamycin and mitomycin-C in advanced stomach cancer]. 1991

C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
GERCOD (groupe d'étude et de recherche sur les cancers de l'ovaire et digestifs) hôpital St-Antoine, Paris, France.

Eighteen patients with advanced gastric cancer were treated with cisplatin 80 mg/m2 d 1, doxorubicin 30 mg/m2 d 3 and mitomycin-C 12 mg/m2 d 3. One complete and 6 partial responses were observed in 17 evaluable patients (41%, confidence interval 17-65%). Median duration of response was 7 months; median survival was 8 months. One death due to toxicity was observed. This combination of 3 active drugs should not be recommended in cases of gastric cancers.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009367 Neoplasm Staging Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. Cancer Staging,Staging, Neoplasm,Tumor Staging,TNM Classification,TNM Staging,TNM Staging System,Classification, TNM,Classifications, TNM,Staging System, TNM,Staging Systems, TNM,Staging, Cancer,Staging, TNM,Staging, Tumor,System, TNM Staging,Systems, TNM Staging,TNM Classifications,TNM Staging Systems
D002945 Cisplatin An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle. Platinum Diamminodichloride,cis-Diamminedichloroplatinum(II),cis-Dichlorodiammineplatinum(II),Biocisplatinum,Dichlorodiammineplatinum,NSC-119875,Platidiam,Platino,Platinol,cis-Diamminedichloroplatinum,cis-Platinum,Diamminodichloride, Platinum,cis Diamminedichloroplatinum,cis Platinum
D004317 Doxorubicin Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN. Adriamycin,Adriablastin,Adriablastine,Adriblastin,Adriblastina,Adriblastine,Adrimedac,DOXO-cell,Doxolem,Doxorubicin Hexal,Doxorubicin Hydrochloride,Doxorubicin NC,Doxorubicina Ferrer Farm,Doxorubicina Funk,Doxorubicina Tedec,Doxorubicine Baxter,Doxotec,Farmiblastina,Myocet,Onkodox,Ribodoxo,Rubex,Urokit Doxo-cell,DOXO cell,Hydrochloride, Doxorubicin,Urokit Doxo cell
D004359 Drug Therapy, Combination Therapy with two or more separate preparations given for a combined effect. Combination Chemotherapy,Polychemotherapy,Chemotherapy, Combination,Combination Drug Therapy,Drug Polytherapy,Therapy, Combination Drug,Chemotherapies, Combination,Combination Chemotherapies,Combination Drug Therapies,Drug Polytherapies,Drug Therapies, Combination,Polychemotherapies,Polytherapies, Drug,Polytherapy, Drug,Therapies, Combination Drug
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
June 1990, Tumori,
C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
May 1984, European journal of cancer & clinical oncology,
C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
April 1983, Gan to kagaku ryoho. Cancer & chemotherapy,
C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
September 1984, The British journal of surgery,
C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
January 1986, Cancer chemotherapy and pharmacology,
C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
July 1985, Gan to kagaku ryoho. Cancer & chemotherapy,
C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
January 1995, Oncology,
C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
April 1978, Cancer treatment reports,
C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
January 1986, Anticancer research,
C Louvet, and A de Gramont, and B Demuynck, and C Varette, and B Lagadec, and J Cady, and M Krulik
August 1990, Nihon Gan Chiryo Gakkai shi,
Copied contents to your clipboard!