[Effect of dibazol (bendazol) on the generative function in rats]. 2007

E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin

The ambiguous influence of bendazol (5 and 160 mg/kg) on the sexual behavior and spermatogenesis of rats was observed in experiments on male rats. An increase in the duration of sexual activity and a decrease of the total amount of spermatozoons were registered irrespective of the course of drug administration in a dose of 5 mg/kg. In males treated with bendazol in a dose of 160 mg/kg, the behavior varied depending on the duration of treatment: the sexual activity decreased upon a 5-day treatment and increased after a 2-month course. The index of spermatogenesis did not depend on the time of administration at 5 or 160 mg/kg, while the spermatozoon mobility was suppressed upon the short-term treatment and increased upon the log-term administration of bendazol.

UI MeSH Term Description Entries
D008297 Male Males
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001562 Benzimidazoles Compounds with a BENZENE fused to IMIDAZOLES.
D012726 Sexual Behavior, Animal Sexual activities of animals. Mating Behavior, Animal,Sex Behavior, Animal,Animal Mating Behavior,Animal Mating Behaviors,Animal Sex Behavior,Animal Sex Behaviors,Animal Sexual Behavior,Animal Sexual Behaviors,Mating Behaviors, Animal,Sex Behaviors, Animal,Sexual Behaviors, Animal
D013091 Spermatogenesis The process of germ cell development in the male from the primordial germ cells, through SPERMATOGONIA; SPERMATOCYTES; SPERMATIDS; to the mature haploid SPERMATOZOA. Spermatocytogenesis,Spermiogenesis
D013094 Spermatozoa Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility. Sperm,Spermatozoon,X-Bearing Sperm,X-Chromosome-Bearing Sperm,Y-Bearing Sperm,Y-Chromosome-Bearing Sperm,Sperm, X-Bearing,Sperm, X-Chromosome-Bearing,Sperm, Y-Bearing,Sperm, Y-Chromosome-Bearing,Sperms, X-Bearing,Sperms, X-Chromosome-Bearing,Sperms, Y-Bearing,Sperms, Y-Chromosome-Bearing,X Bearing Sperm,X Chromosome Bearing Sperm,X-Bearing Sperms,X-Chromosome-Bearing Sperms,Y Bearing Sperm,Y Chromosome Bearing Sperm,Y-Bearing Sperms,Y-Chromosome-Bearing Sperms
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
January 2012, Eksperimental'naia i klinicheskaia farmakologiia,
E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
January 1958, Farmakologiia i toksikologiia,
E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
May 1980, Biulleten' eksperimental'noi biologii i meditsiny,
E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
January 1954, Farmakologiia i toksikologiia,
E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
January 2004, Eksperimental'naia i klinicheskaia farmakologiia,
E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
January 1969, Farmakologiia i toksikologiia,
E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
January 1954, Farmakologiia i toksikologiia,
E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
January 1967, Gigiena truda i professional'nye zabolevaniia,
E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
July 1973, Gigiena i sanitariia,
E A Kuzubova, and A A Spasov, and L I Bugaeva, and M V Bukatin
January 1966, Farmakologiia i toksikologiia,
Copied contents to your clipboard!