BIOMAT Database Logo BIOMAT Database Logo

[Lactase deficiency and lactose intolerance-related symptoms in adult healthy subjects from western France]. 1991

D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
Groupe Fonctions Digestives et Nutrition, Centre de Recherches sur Volontaires, CHU Nord, Nantes.

The prevalence of lactase deficiency (LD) and lactose intolerance is not well known in France. Using breath hydrogen and methane analysis after 50 g oral lactose load, we investigated the prevalences of LD, lactose intolerance, and methane producer status in 102 healthy adults born in western France, and we examined the relationships between these parameters and the daily milk consumption. In 10 subjects with LD and lactose intolerance, we studied the reproducibility of the lactose hydrogen breath test results for the diagnosis of LD and lactose intolerance and estimated the quantity of lactose malabsorbed in comparison with the lactulose hydrogen breath test. The prevalence of LD was 23.4 percent and symptoms of lactose intolerance were observed in 50 percent of the 24 subjects with LD. The daily milk consumption was not significantly different in the 24 subjects with LD and in the 78 subjects without LD (281 +/- 197 vs 303 +/- 217 ml/24 h). The prevalence of methane producer status was 42.1 percent. The symptomatic group of lactose malabsorbers (n = 12) was characterized by a shorter lactose mouth to caecum transit time (39 +/- 20 vs 88 +/- 48 min; P less than 0.05), and more marked hydrogen production (6.1 +/- 2.3 vs 3.4 +/- 2.4 10(3) ppm.min; P less than 0.04). In the 10 subjects with LD and lactose intolerance, the hydrogen breath test was reproducible for diagnosis of LD and lactose intolerance, and for hydrogen production. The quantity of lactose malabsorbed was 60 percent. In France, symptoms of lactose intolerance are not severe and do not affect the daily consumption of milk and dairy products.

UI MeSH Term Description Entries
D007787 Lactose Intolerance The condition resulting from the absence or deficiency of LACTASE in the MUCOSA cells of the GASTROINTESTINAL TRACT, and the inability to break down LACTOSE in milk for ABSORPTION. Bacterial fermentation of the unabsorbed lactose leads to symptoms that range from a mild indigestion (DYSPEPSIA) to severe DIARRHEA. Lactose intolerance may be an inborn error or acquired. Lactose Malabsorption,Alactasia,Dairy Product Intolerance,Hypolactasia,Milk Sugar Intolerance,Intolerance, Lactose,Malabsorption, Lactose
D007789 Lactose Tolerance Test A measure of a patient's ability to break down lactose. Lactose Tolerance Tests,Test, Lactose Tolerance,Tests, Lactose Tolerance,Tolerance Test, Lactose,Tolerance Tests, Lactose
D008297 Male Males
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D003967 Diarrhea An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight. Diarrheas
D005260 Female Females
D005414 Flatulence Production or presence of gas in the gastrointestinal tract which may be expelled through the anus. Flatus
D005602 France A country in western Europe bordered by the Atlantic Ocean, the English Channel, the Mediterranean Sea, and the countries of Belgium, Germany, Italy, Spain, Switzerland, the principalities of Andorra and Monaco, and by the duchy of Luxembourg. Its capital is Paris. Corsica,Saint Pierre and Miquelon,Miquelon and Saint Pierre,Miquelon and St. Pierre,St. Pierre and Miquelon
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006859 Hydrogen The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas. Protium,Hydrogen-1

Related Publications

D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
[Lactose intolerance and lactase deficiency in adult patients in Curacao].
June 1972, Nederlands tijdschrift voor geneeskunde,
D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
Lactose intolerance and lactase deficiency in children.
October 1994, Current opinion in pediatrics,
D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
[Lactose intolerance caused by lactase deficiency].
September 1974, Archives francaises des maladies de l'appareil digestif,
D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
Intestinal lactase deficiency and lactose intolerance in adults.
March 1966, JAMA,
D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
Intestinal lactase deficiency and lactose intolerance in adults. Preliminary report.
April 1968, Gastroenterology,
D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
INTESTINAL LACTASE DEFICIENCY AND LACTOSE INTOLERANCE IN ADULTS. PRELIMINARY REPORT.
October 1963, Gastroenterology,
D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
[Milk intolerance, lactose intolerance and lactase deficiency in partial resection of the stomach].
May 1976, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen,
D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
Lactose load and abdominal symptoms: should milk be withdrawn from healthy subjects with low lactase levels?
January 1973, Gastroenterology,
D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
A racial difference in incidence of lactase deficiency. A survey of milk intolerance and lactase deficiency in healthy adult males.
September 1966, JAMA,
D Cloarec, and S Gouilloud, and F Bornet, and S Bruley des Varannes, and Y Bizais, and J P Galmiche
Lactase Non-persistence and Lactose Intolerance.
May 2017, Current gastroenterology reports,
Copied contents to your clipboard!