[Mechanical properties of the lungs in bronchial asthma]. 2007

K F Tetenev, and T N Bodrova, and F F Tetenev

OBJECTIVE To evaluate basic parameters of elastic and nonelastic resistance of the lungs in patients with bronchial asthma (BA) with reference to severity of pulmonary ventilation disorder (PVD). METHODS PVD was diagnosed in 92 BA patients aged 18 to 55 years (mean age 42 years, 50 males and 40 females). By PVD severity the patients were divided into 4 groups. The control group consisted of 65 healthy volunteers aged 18-54 years (mean age 45.6 years, 30 males and 35 females). PVD degree was assessed by reduction of respiratory capacity (RC) and forced expiratory volume per second (FEV1), volumes of the lungs, ventilation speed, bronchial resistance (Raw), total respiratory performance, total nonelastic resistance (TNR), total nonelastic pressure, dynamic lung compliance, static lung compliance (Cstat), elastic lung traction (ELT). RESULTS A RC fall in groups 2-4 was less significant than FEV1 reduction. Raw was elevated in all the groups: in group 2 the rise was more than in group 1, but in groups 3 and 4 the rise was similar. TNR at inhalation and exhalation increased from group 1 to group 3, was high in group 4. Cstat and ELT were similarly subnormal in all the groups. CONCLUSIONS Elevation of bronchial resistance does not influence PVD severity. Lowering of FEV1 only partially is related with Raw elevation. Subnormal lung compliance may represent a compensatory reaction directed to overcoming valvular bronchial obstruction and maintenance of normal lung ventilation. Low lung traction may result from high mechanical activity of the lungs in condition of its estimation.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D012123 Pulmonary Ventilation The total volume of gas inspired or expired per unit of time, usually measured in liters per minute. Respiratory Airflow,Ventilation Tests,Ventilation, Pulmonary,Expiratory Airflow,Airflow, Expiratory,Airflow, Respiratory,Test, Ventilation,Tests, Ventilation,Ventilation Test
D004548 Elasticity Resistance and recovery from distortion of shape.
D005260 Female Females
D005541 Forced Expiratory Volume Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity. Forced Vital Capacity, Timed,Timed Vital Capacity,Vital Capacity, Timed,FEVt,Capacities, Timed Vital,Capacity, Timed Vital,Expiratory Volume, Forced,Expiratory Volumes, Forced,Forced Expiratory Volumes,Timed Vital Capacities,Vital Capacities, Timed,Volume, Forced Expiratory,Volumes, Forced Expiratory
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000403 Airway Resistance Physiologically, the opposition to flow of air caused by the forces of friction. As a part of pulmonary function testing, it is the ratio of driving pressure to the rate of air flow. Airway Resistances,Resistance, Airway,Resistances, Airway

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