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In order to investigate the influence of respiratory frequency in the measurement of specific airway conductance (sGaw) during non-panting breathing, we examined specific airway conductance using a body plethysmograph (BX-82, Minato) in 20 stable pulmonary emphysema patients and 19 normal control subjects. Our body plethysmograph device can measure sGaw automatically without panting by making various corrections using a 16-bit microcomputer. We measured sGaw first at a flow of 0.5 L/sec during both inspiratory and expiratory ventilatory phases, then the respiratory frequency was changed from 0.5 to 1.0, 1.5 and 2.0 Hz. In normal control subjects sGaw, tidal volume and mouth flow significantly changed by increasing respiratory frequency, and there was a significant correlation between sGaw and mouth flow. In pulmonary emphysema patients, tidal volume decreased significantly by increasing respiratory frequency, and there was a significant correlation between sGaw and tidal volume, but sGaw and mouth flow did not change significantly by increasing respiratory frequency. These results suggest that specific airway conductance is influenced by respiratory frequency, possibly due to the change in tidal volume and mouth flow. It is necessary to standardize respiratory frequencies and mouth flows in the measurement of specific airway conductance during non-panting breathing.
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T Suyama, and
H Aoki, and
K Matsuki, and
S Hasegawa
December 1984,
Journal of applied physiology: respiratory, environmental and exercise physiology,
M Inoue, and
T Honma, and
T Saitoh, and
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H Aoki, and
K Matsuki, and
S Hasegawa
January 1993,
Nihon Kyobu Shikkan Gakkai zasshi,
M Inoue, and
T Honma, and
T Saitoh, and
T Suyama, and
H Aoki, and
K Matsuki, and
S Hasegawa
March 2014,
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M Inoue, and
T Honma, and
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K Matsuki, and
S Hasegawa
July 1992,
Nihon Kyobu Shikkan Gakkai zasshi,
M Inoue, and
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S Hasegawa
June 1983,
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M Inoue, and
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S Hasegawa
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September 1987,
Nihon Kyobu Shikkan Gakkai zasshi,
M Inoue, and
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May 1988,
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