Biomaterial Database

[Use of bepridil in patients with angina pectoris]. 1991

E A Nekrutman, and V P Lupanov, and A A Liakishev, and Ia A Podinovskaia

The efficacy of the calcium antagonist bepridil given in a dose of 200-400 mg/day was evaluated in 22 patients with Functional Classes II-III stable angina pectoris. In addition to clinical assessments, repeated bicycle ergometric exercise tests were performed in the patients. The agent was found to be highly potent, well tolerated, and to cause no grave adverse effects.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000787	Angina Pectoris	The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.	Angor Pectoris,Stenocardia,Stenocardias
D015444	Exercise	Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.	Aerobic Exercise,Exercise, Aerobic,Exercise, Isometric,Exercise, Physical,Isometric Exercise,Physical Activity,Acute Exercise,Exercise Training,Activities, Physical,Activity, Physical,Acute Exercises,Aerobic Exercises,Exercise Trainings,Exercise, Acute,Exercises,Exercises, Acute,Exercises, Aerobic,Exercises, Isometric,Exercises, Physical,Isometric Exercises,Physical Activities,Physical Exercise,Physical Exercises,Training, Exercise,Trainings, Exercise
D015764	Bepridil	A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.	1978-CERM,Bedapin,Bepadin,Bepridil Monohydrochloride,Bepridil Monohydrochloride, Monohydrate,Bepridil Monohydrochloride, alpha-Isomer,Bepridil, (+)-Isomer,Bepridil, (+-)-Isomer,Bepridil, (-)-Isomer,Bepridil, alpha-Isomer,CERM-1978,Cordium,Unicordium,Vascor,1978 CERM,1978CERM,Bepridil Monohydrochloride, alpha Isomer,Bepridil, alpha Isomer,CERM 1978,CERM1978,Monohydrochloride, Bepridil,Monohydrochloride, alpha-Isomer Bepridil