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Cardiolipin antibodies are detected in the sera from patients having a wide range of clinical manifestations, including venous and arterial thrombosis, obstetric abnormality, damaged CHS and diseased vascular wall. To clarify the clinical value of cardiolipin antibodies, 21 patients with non-specific aortic arteritis were studied. The antibodies were determined by enzyme immunoassay. Their higher levels were found in 5 (24%) patients. The patients who were positive for cardiolipin antibodies showed a significant increase in the incidence of occlusive lesions (p less than 0.001) and a moderate increase in that of valvular heart diseases. The findings suggest that cardiolipin antibodies might contribute to the pathogenesis of non-specific of aortic arteritis.
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L Z Aleksandrova
January 1995,
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L Z Aleksandrova
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L Z Aleksandrova
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E L Naconov, and
G G Arabidze, and
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E L Naconov, and
G G Arabidze, and
A B Sugraliev, and
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E L Naconov, and
G G Arabidze, and
A B Sugraliev, and
V N Kovalev, and
L Z Aleksandrova
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E L Naconov, and
G G Arabidze, and
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V N Kovalev, and
L Z Aleksandrova
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