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OBJECTIVE To summarize the experiences of cardiopulmonary bypass (CPB) techniques in 15 patients of orthotopic heart transplantation. METHODS All patients received mild hypothermia and high flow rate perfusion. Effective strategies were taken to protect myocardium, lung, kidney, and blood conservation. The donor hearts were arrested with aorto perfusion using 1 000 ml St. Thomas solution at 4 degrees C, perfused with 1 000 ml University of Wiscosin (UW) solution or Histidin-Tryptophan-Ketoglutarat (HTK) solution at 4 degrees C, and then preserved in ice saline. Ice mud was covered on the donor heart during anastomosis. Low potassium cardioplegia solution was perfused before the unclamping of aorta. RESULTS The CPB time was (165.2 +/- 22. 8) min, the warm ischemia time was ( 7. 7 +/- 1. 7) min, and the cold ischemia time was ( 142. 4 +/- 11. 5) min. Heart beats was automatically recovered in 10 patients, and was recovered upon defibrillation in 5 patients. Left ventricular ejection fractions were (64. 1 +/- 4. 6) % after one month. All patients survived. CONCLUSIONS Proper CPB management and effective donor heart protection are essential to guarantee the success of heart transplantation.
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
August 2004,
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences,
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
March 2011,
Singapore medical journal,
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
March 2001,
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation,
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
January 1976,
Scandinavian journal of thoracic and cardiovascular surgery,
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
March 1997,
Perfusion,
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
December 1961,
Scottish medical journal,
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
January 1958,
Anesthesiology,
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
April 1960,
The American surgeon,
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
May 1962,
El Dia medico,
Fei-Long Hei, and
Shi-Gang Wang, and
Cun Long
January 2018,
ASAIO journal (American Society for Artificial Internal Organs : 1992),
