Mediastinal pleomorphic liposarcoma diagnosed by fine needle aspiration biopsy: a case report. 2007

Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
Pathology Unit, Hospital General de México. monicaromero@att.net.mx

BACKGROUND Progress in radiology and pathology for diagnosing mediastinal tumors has R been made in recent decades, thanks to the use of fine needle aspiration biopsy (FNAB) guided by computed tomography, which has replaced mediastinoscopy and open biopsies. METHODS A 66-year-old male had a history o productive coughing with mucopurulent expectoration, progressive dyspnea, arthralgias, myalgias, astenia and adynamia for the previous 3 months. A CT scan and magnetic resonance imaging revealed a poorly limited tumor mass ofheterogeneous den sity in the anterior mediastinum. FNAB of the tumor mass showed malignant cells compatible with liposarcoma. CONCLUSLON: Of the several types of mesenchymal mediastinal neoplasms, liposarcoma is the most important. Many of them are seen in adults, and <10 cases have been diagnosed in children. The symptoms are related to compression of the nearby airways. Usually liposarcomas are yellow, lobed tumors without capsules that infiltrate adjacent organs and tissues. Microscopically, they have the same histologic spectrum as tumors originating in other sites. Thus, it is common to observe all the histologic varieties of soft tissue liposarcomas. The identification of lipoblasts is the key to the correct diagnosis in FNAB material.

UI MeSH Term Description Entries
D008080 Liposarcoma A malignant tumor derived from primitive or embryonal lipoblastic cells. It may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid (LIPOSARCOMA, MYXOID), round-celled, or pleomorphic, usually in association with a rich network of capillaries. Recurrences are common and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces. (From Dorland, 27th ed; Stedman, 25th ed) Liposarcoma, Dedifferentiated,Liposarcoma, Pleomorphic,Atypical Lipomatous Tumor,Liposarcoma, Well Differentiated,Well Differentiated Liposarcoma,Atypical Lipomatous Tumors,Dedifferentiated Liposarcoma,Dedifferentiated Liposarcomas,Lipomatous Tumor, Atypical,Liposarcomas,Pleomorphic Liposarcoma,Pleomorphic Liposarcomas,Well Differentiated Liposarcomas
D008279 Magnetic Resonance Imaging Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques. Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D008297 Male Males
D008479 Mediastinal Neoplasms Tumors or cancer of the MEDIASTINUM. Cancer of Mediastinum,Mediastinal Cancer,Cancer of the Mediastinum,Mediastinum Cancer,Mediastinum Neoplasms,Neoplasms, Mediastinal,Cancer, Mediastinal,Cancer, Mediastinum,Cancers, Mediastinal,Cancers, Mediastinum,Mediastinal Cancers,Mediastinal Neoplasm,Mediastinum Cancers,Mediastinum Neoplasm,Neoplasm, Mediastinal,Neoplasm, Mediastinum,Neoplasms, Mediastinum
D002467 Cell Nucleus Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed) Cell Nuclei,Nuclei, Cell,Nucleus, Cell
D003593 Cytoplasm The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990) Protoplasm,Cytoplasms,Protoplasms
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D044963 Biopsy, Fine-Needle Using fine needles (finer than 22-gauge) to remove tissue or fluid specimens from the living body for examination in the pathology laboratory and for disease diagnosis. Aspiration Biopsy, Fine-Needle,Fine Needle Biopsy,Fine-Needle Aspiration,Aspiration Biopsies, Fine-Needle,Aspiration Biopsy, Fine Needle,Aspiration, Fine-Needle,Aspirations, Fine-Needle,Biopsies, Fine Needle,Biopsies, Fine-Needle,Biopsies, Fine-Needle Aspiration,Biopsy, Fine Needle,Biopsy, Fine-Needle Aspiration,Fine Needle Aspiration,Fine Needle Biopsies,Fine-Needle Aspiration Biopsies,Fine-Needle Aspiration Biopsy,Fine-Needle Aspirations,Fine-Needle Biopsies,Fine-Needle Biopsy,Needle Biopsies, Fine,Needle Biopsy, Fine
D017809 Fatal Outcome Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept. Fatal Outcomes,Outcome, Fatal,Outcomes, Fatal

Related Publications

Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
January 2022, Diagnostic cytopathology,
Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
January 2007, Acta cytologica,
Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
January 1985, Acta cytologica,
Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
January 1978, Acta cytologica,
Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
January 1999, Acta cytologica,
Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
February 2010, Diagnostic cytopathology,
Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
January 1983, Acta cytologica,
Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
January 1984, Acta cytologica,
Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
October 2014, Diagnostic cytopathology,
Mónica B Romero-Guadarrama, and Silvia Jiménez-Becerra, and Marco A Durán-Padilla, and Ana Cecilia Santiago-Prieto, and Humberto Cruz-Ortiz, and Virginia Novelo-Retana
October 1998, Diagnostic cytopathology,
Copied contents to your clipboard!