-transparent.png){kind=logo}
Literature data on respectively botany, chemistry, ethnopharmacology, pharmacology and toxicology of Azadirachta indica A. Juss. (Meliaceae) are reviewed and evaluated. In traditional literature, preparations of the tree are claimed to be vulnerable in wide spectrum of diseases. Especially for inflammation-related diseases a good correlation is found with the results of recent experimental investigations. In addition, a variety of other biological activities are reported. Most frequently the effects can be attributed to compounds representing the structural classes of the limonoids, phenolics and macromolecules. Reported toxicity of preparations and isolated compounds are low, except for the seed oil. In conclusion, A. indica can be regarded as a valuable plant source for the rationalisation of its use in traditional medicine and for modern drug development.
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
January 2022,
Brazilian journal of biology = Revista brasleira de biologia,
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
July 2019,
Natural product research,
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
December 2003,
Acta pharmaceutica (Zagreb, Croatia),
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
September 2008,
International journal of molecular sciences,
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
February 2021,
Chronobiology international,
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
December 1988,
Indian journal of malariology,
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
May 1996,
Journal of ethnopharmacology,
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
January 2004,
Zeitschrift fur Naturforschung. C, Journal of biosciences,
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
July 2016,
G3 (Bethesda, Md.),
J M van der Nat, and
W G van der Sluis, and
K T de Silva, and
R P Labadie
January 1999,
Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products. Progres dans la chimie des substances organiques naturelles,
