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The stimulating effect of theophylline on the plasma renin activity (PRA) under beta-receptor blockade by propranolol or practolol was investigated in 27 patients with essential hypertension of degree I-II. After propranolol and also practolol PRA decreased about thirty per cent of the basal value, increased however by the factor of 2 to 3 after application of theophylline, in spite of the blockade of the beta-receptors indicated by a slight decrease of systolic blood pressure and heart rate. The effect of propranolol and practolol on the basal PRA was not different. Our results show the possibility, to stimulate renin secretion despite blockade of beta receptors by propranolol or practolol, respectively.
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
September 1974,
Zeitschrift fur klinische Chemie und klinische Biochemie,
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
September 1973,
Klinische Wochenschrift,
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
December 1976,
Casopis lekaru ceskych,
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
September 1977,
Nihon Jinzo Gakkai shi,
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
February 1979,
Monatsschrift fur Kinderheilkunde,
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
January 1976,
Annales d'endocrinologie,
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
January 1979,
Annales d'endocrinologie,
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
July 1981,
Kokyu to junkan. Respiration & circulation,
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
November 1975,
Deutsche medizinische Wochenschrift (1946),
J Zehner, and
D Klaus, and
F Klumpp, and
R Lemke
July 1978,
Casopis lekaru ceskych,
