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The data on the status of immunoregulation in 144 children with gastroduodenal pathology are provided as are indications for differentiated immunomodulatory therapy. As many as 100 children with celiac disease treated by means of long administration of the gluten-free diet were examined for the immunogenetic aspects and changes in the immune status. The authors demonstrate the incidence of recurrent intestinal disorders among 24 children with primary immunodeficiency states.
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