Biomaterial Database

[Effects of stimulation of arcuate nucleus on intragastric pressure and peripheral pathway analysis in rats]. 1991

R Ma, and G Y Xu

Department of Physiology, Anhui Medical University, Hefei.

The effect of electrical stimulation of arcuate nucleus (ARC) on intragastric pressure (IGP) was examined on 68 Wistar rats anaesthetized with urethan. The results were as follows: (1) Stimulation of ARC could induce an obvious decrease of IGP. (2) This effect was not blocked by atropine but partially by vagotomy. (3) Extirpation of celiac neural plexus or intramuscular injection of phentolamine could obviously reduce the suppression of IGP induced by ARC stimulation, but intramuscular injection of propranolol had no such effect. (4) After vagotomy plus extirpation of celiac neural plexus, IGP could still be made a decrease by stimulating ARC. In view of the present investigation, it is suggested that (1) Both sympathetic nerve and vagus are involved in the reduction of IGP induced by ARC stimulation, the former and the latter routes being respectively mediated by alpha-adrenoceptor and non-cholinergic, non-adrenergic fibres. (2) Humoral factors may be also involved in this effect of ARC stimulation.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D011312	Pressure	A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Pressures
D002447	Celiac Plexus	A complex network of nerve fibers including sympathetic and parasympathetic efferents and visceral afferents. The celiac plexus is the largest of the autonomic plexuses and is located in the abdomen surrounding the celiac and superior mesenteric arteries.	Coeliac Plexus,Plexus Coeliacus,Solar Plexus,Coeliacus, Plexus,Plexus, Celiac,Plexus, Coeliac,Plexus, Solar
D004558	Electric Stimulation	Use of electric potential or currents to elicit biological responses.	Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D005260	Female		Females
D005769	Gastrointestinal Motility	The motor activity of the GASTROINTESTINAL TRACT.	Intestinal Motility,Gastrointestinal Motilities,Intestinal Motilities,Motilities, Gastrointestinal,Motilities, Intestinal,Motility, Gastrointestinal,Motility, Intestinal
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001111	Arcuate Nucleus of Hypothalamus	A nucleus located in the middle hypothalamus in the most ventral part of the THIRD VENTRICLE near the entrance of the infundibular recess. Its small cells are in close contact with the EPENDYMA.	Arcuate Nucleus,Infundibular Nucleus,Hypothalamus Arcuate Nucleus,Nucleus, Arcuate,Nucleus, Infundibular
D013270	Stomach	An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.	Stomachs
D014628	Vagotomy	The interruption or removal of any part of the vagus (10th cranial) nerve. Vagotomy may be performed for research or for therapeutic purposes.	Vagotomies