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A 17-month-old child with acute biphenotypic (pre B-ALL/myelomonocytic) leukemia is reported. Extensive cytogenetic analysis performed at various stages of the disease revealed a clonal evolution at the time of initial diagnosis with two types of abnormal clones, one with trisomy 22 and two other related clones with trisomy 22 plus partial trisomy of the long arm of chromosome 1 associated with the telomeric segment of either chromosome 20q or 21p. At the time of relapse the only abnormal clone involved trisomy 22 and partial trisomy of 1q, but this time in association with the telomeric segment of 14p. The unique feature of these translocations is discussed and the possibility of the correlation between the different chromosomal abnormalities and the expression of biphenotypic markers is raised.
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
March 2003,
Cancer genetics and cytogenetics,
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
January 1986,
Pediatric pathology,
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
January 1984,
Pediatric pathology,
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
March 1994,
HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues,
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
June 2013,
BMJ case reports,
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
September 2004,
Leukemia,
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
September 1977,
Pediatria polska,
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
April 1972,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
June 2003,
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons,
S Ben-Neriah, and
A Abramov, and
I Lerer, and
A Polliack, and
R Leizerowitz, and
R Rabinowitz, and
D Abeliovich
January 2000,
Leukemia,
