Current concepts and techniques in pterygium treatment. 2007

Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
Singapore National Eye Centre, Singapore. leopk@pacific.net.sg

OBJECTIVE Pterygium is a common ocular disorder in many parts of the world. At present, there is a wide variety of surgical methods but very few clinical guidelines on the optimal treatment of primary or recurrent pterygium. The purpose of this review is to summarize the more recent and relevant studies on pterygium treatment. RESULTS The primary aim is to excise the pterygium and prevent its recurrence. As bare sclera excision is associated with a high recurrence rate, pterygium excision is often combined with conjunctival autograft, mitomycin C, beta-irradiation or other adjunctive therapies to reduce recurrence rates. There is currently, however, no consensus regarding the ideal treatment for the disease. Comparability between studies is also hampered by the various definitions of pterygium recurrence. CONCLUSIONS This article reviews the current concepts and techniques used for the treatment of pterygium. Conjunctival autografting and mitomycin C application are the most commonly used methods for preventing recurrences. The use of mitomycin C and beta-irradiation should be used judiciously because of the potential long-term risk of sight-threatening complications. Additional clinical trials should be performed to evaluate the relative efficacies and long-term safety of the various treatment modalities.

UI MeSH Term Description Entries
D011625 Pterygium An abnormal triangular fold of membrane in the interpalpebral fissure, extending from the conjunctiva to the cornea, being immovably united to the cornea at its apex, firmly attached to the sclera throughout its middle portion, and merged with the conjunctiva at its base. (Dorland, 27th ed) Pterygiums
D003228 Conjunctiva The mucous membrane that covers the posterior surface of the eyelids and the anterior pericorneal surface of the eyeball. Bulbar Conjunctiva,Palpebral Conjunctiva,Plica Semilunaris of Conjunctiva,Plicae Semilunares of Conjunctiva,Tunica Conjunctiva,Conjunctiva, Bulbar,Conjunctiva, Palpebral,Conjunctivas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013508 Ophthalmologic Surgical Procedures Surgery performed on the eye or any of its parts. Ophthalmologic Surgical Procedure,Ophthalmological Surgical Procedures,Procedure, Ophthalmologic Surgical,Procedures, Ophthalmologic Surgical,Surgical Procedure, Ophthalmologic,Surgical Procedures, Ophthalmologic,Ophthalmological Surgical Procedure,Procedure, Ophthalmological Surgical,Procedures, Ophthalmological Surgical,Surgical Procedure, Ophthalmological,Surgical Procedures, Ophthalmological
D017024 Chemotherapy, Adjuvant Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment. Adjuvant Chemotherapy,Drug Therapy, Adjuvant,Adjuvant Drug Therapy
D055502 Secondary Prevention The prevention of recurrences or exacerbations of a disease or complications of its therapy. Disease Prevention, Secondary,Early Therapy,Relapse Prevention,Secondary Disease Prevention,Disease Preventions, Secondary,Early Therapies,Prevention, Relapse,Prevention, Secondary,Prevention, Secondary Disease,Preventions, Relapse,Preventions, Secondary,Preventions, Secondary Disease,Relapse Preventions,Secondary Disease Preventions,Secondary Preventions,Therapies, Early,Therapy, Early
D018714 Radiotherapy, Adjuvant Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment. Adjuvant Radiotherapy,Adjuvant Radiotherapies,Radiotherapies, Adjuvant

Related Publications

Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
January 2009, International ophthalmology clinics,
Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
January 1999, Surgical technology international,
Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
July 1977, The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society,
Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
August 2005, Current opinion in ophthalmology,
Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
January 2008, The ocular surface,
Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
August 2002, Current opinion in ophthalmology,
Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
April 2006, Clinics in podiatric medicine and surgery,
Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
July 2006, The Orthopedic clinics of North America,
Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
December 2005, The journal of investigative dermatology. Symposium proceedings,
Leonard P K Ang, and Jocelyn L L Chua, and Donald T H Tan
December 1953, International abstracts of surgery,
Copied contents to your clipboard!