Evaluation of Taenia solium and Taenia crassiceps cysticercal antigens for immunodiagnosis of neurocysticercosis using ELISA on cerebrospinal fluid samples. 2007

Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
Departamento de Patologia Clínica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP.

The efficacy of whole parasite and vesicular fluid antigen extracts from Taenia solium and Taenia crassiceps cysticerci for immunodiagnosis of neurocysticercosis was evaluated using ELISA on cerebrospinal fluid samples. Anticysticercal IgG antibodies were assayed in cerebrospinal fluid samples from 23 patients with neurocysticercosis and 35 patients with other neurological disorders. The ELISA reaction for the whole Taenia solium cysticercal extract showed 91.3% sensitivity and 94.3% specificity, whereas the sensitivity and specificity of the ELISA for the whole Taenia crassiceps cysticercal extract were 87% and 94.3%, respectively. The ELISA reactions for vesicular fluid from Taenia solium or Taenia crassiceps showed 91.3% sensitivity and 97.1% specificity. Considering the results obtained from the four antigen preparations, vesicular fluid from Taenia solium and Taenia crassiceps cysticerci may be useful as a source of antigens for immunological reactions that are used for detecting specific antibodies in cerebrospinal fluid samples from patients with neurocysticercosis.

UI MeSH Term Description Entries
D007074 Immunoglobulin G The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B. Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D004797 Enzyme-Linked Immunosorbent Assay An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. ELISA,Assay, Enzyme-Linked Immunosorbent,Assays, Enzyme-Linked Immunosorbent,Enzyme Linked Immunosorbent Assay,Enzyme-Linked Immunosorbent Assays,Immunosorbent Assay, Enzyme-Linked,Immunosorbent Assays, Enzyme-Linked
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000909 Antibodies, Helminth Immunoglobulins produced in a response to HELMINTH ANTIGENS. Helminth Antibodies
D000947 Antigens, Helminth Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes. Helminth Antigens
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity
D013621 Taenia A genus of large tapeworms. Taeniarhynchus,Taenias
D015203 Reproducibility of Results The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results. Reliability and Validity,Reliability of Result,Reproducibility Of Result,Reproducibility of Finding,Validity of Result,Validity of Results,Face Validity,Reliability (Epidemiology),Reliability of Results,Reproducibility of Findings,Test-Retest Reliability,Validity (Epidemiology),Finding Reproducibilities,Finding Reproducibility,Of Result, Reproducibility,Of Results, Reproducibility,Reliabilities, Test-Retest,Reliability, Test-Retest,Result Reliabilities,Result Reliability,Result Validities,Result Validity,Result, Reproducibility Of,Results, Reproducibility Of,Test Retest Reliability,Validity and Reliability,Validity, Face
D016022 Case-Control Studies Comparisons that start with the identification of persons with the disease or outcome of interest and a control (comparison, referent) group without the disease or outcome of interest. The relationship of an attribute is examined by comparing both groups with regard to the frequency or levels of outcome over time. Case-Base Studies,Case-Comparison Studies,Case-Referent Studies,Matched Case-Control Studies,Nested Case-Control Studies,Case Control Studies,Case-Compeer Studies,Case-Referrent Studies,Case Base Studies,Case Comparison Studies,Case Control Study,Case Referent Studies,Case Referrent Studies,Case-Comparison Study,Case-Control Studies, Matched,Case-Control Studies, Nested,Case-Control Study,Case-Control Study, Matched,Case-Control Study, Nested,Case-Referent Study,Case-Referrent Study,Matched Case Control Studies,Matched Case-Control Study,Nested Case Control Studies,Nested Case-Control Study,Studies, Case Control,Studies, Case-Base,Studies, Case-Comparison,Studies, Case-Compeer,Studies, Case-Control,Studies, Case-Referent,Studies, Case-Referrent,Studies, Matched Case-Control,Studies, Nested Case-Control,Study, Case Control,Study, Case-Comparison,Study, Case-Control,Study, Case-Referent,Study, Case-Referrent,Study, Matched Case-Control,Study, Nested Case-Control

Related Publications

Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
October 2005, Tropical medicine & international health : TM & IH,
Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
January 2000, Journal of clinical microbiology,
Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
March 2000, Arquivos de neuro-psiquiatria,
Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
September 1997, The American journal of tropical medicine and hygiene,
Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
September 1990, Archives of pathology & laboratory medicine,
Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
January 2002, Clinical and diagnostic laboratory immunology,
Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
February 2020, Parasitology,
Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
March 2001, Tropical medicine & international health : TM & IH,
Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
February 2000, Veterinary parasitology,
Lisandra Akemi Suzuki, and Gisele Cristina Arruda, and Elizabeth Maria Aparecida Barasnevicius Quagliato, and Qláudio Lúcio Rossi
July 1989, The American journal of tropical medicine and hygiene,
Copied contents to your clipboard!