Alcohol does not affect dark adaptation or luminance increment thresholds. 2007

Sarah A Khan, and Brian Timney
Department of Psychology, The University of Western Ontario, Social Science Centre, Room 6254, London, Ontario, Canada N6A 5C2. skhan5@uwo.ca

OBJECTIVE It has been proposed that alcohol might induce within the retina a state akin to dark adaptation. However, the evidence to support this proposal is quite indirect. Another possibility is that alcohol might affect retinal gain control rather than sensitivity. To investigate these proposals psychophysically, we measured dark adaptation functions and increment thresholds with the increment threshold procedure in individuals with moderate blood alcohol concentrations (BACs). METHODS Individuals were tested under both alcohol and no-alcohol conditions (BAC approximately .08%). In Experiment 1, thresholds for the detection of a parafoveal target were measured over a 25-minute period following a 3-minute bleach in six males. In Experiment 2, the cone dark adaptation function of four males was examined in more detail for a foveal target following bleaching at three different levels. In Experiment 3, we measured the thresholds of nine men for a small target superimposed on a background field that varied over 4 log units in luminance. RESULTS We found no effects of alcohol on either the rod or the cone portion of the dark adaptation curve or on increment thresholds. CONCLUSIONS Together, these data indicate that moderate alcohol ingestion does not affect the recovery of visual sensitivity in the dark nor does it affect gain control at the retinal level.

UI MeSH Term Description Entries
D008297 Male Males
D010364 Pattern Recognition, Visual Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs. Recognition, Visual Pattern,Visual Pattern Recognition
D011930 Reaction Time The time from the onset of a stimulus until a response is observed. Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D012160 Retina The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent. Ora Serrata
D003623 Dark Adaptation Adjustment of the eyes under conditions of low light. The sensitivity of the eye to light is increased during dark adaptation. Scotopic Adaptation,Adaptation, Dark,Adaptation, Scotopic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000428 Alcohol Drinking Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking. Alcohol Consumption,Alcohol Intake,Drinking, Alcohol,Alcohol Drinking Habits,Alcohol Drinking Habit,Alcohol Intakes,Consumption, Alcohol,Drinking Habit, Alcohol,Habit, Alcohol Drinking,Habits, Alcohol Drinking,Intake, Alcohol
D000431 Ethanol A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES. Alcohol, Ethyl,Absolute Alcohol,Grain Alcohol,Alcohol, Absolute,Alcohol, Grain,Ethyl Alcohol

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