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Measurement of macular pigment optical density using two different heterochromatic flicker photometers. 2007

Edward Loane, and Jim Stack, and Stephen Beatty, and John M Nolan
Macular Pigment Research Group, Department of Chemical & Life Sciences, Waterford Institute of Technology, Waterford, Ireland. eloane@wit.ie

OBJECTIVE To compare macular pigment optical density using two different heterochromatic flicker photometers. METHODS We measured macular pigment optical density in 121 healthy subjects using heterochromatic flicker photometry. RESULTS The mean (+/-SD) macular pigment optical density measured using the Maculometer was 0.394 (+/-0.170), and that using the Densitometer was 0.395 (+/-0.189). The difference in measurements on each instrument was influenced by age and macular pigment levels. CONCLUSIONS On average, there is no difference in measurements provided by these two instruments. The Maculometer tends to underestimate macular pigment in older subjects and/or those with higher macular pigment compared with the Densitometer.

UI MeSH Term Description Entries
D008268 Macular Degeneration Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms. Maculopathy,Maculopathy, Age-Related,Age-Related Macular Degeneration,Age-Related Maculopathies,Age-Related Maculopathy,Macular Degeneration, Age-Related,Macular Dystrophy,Maculopathies, Age-Related,Age Related Macular Degeneration,Age Related Maculopathies,Age Related Maculopathy,Age-Related Macular Degenerations,Degeneration, Macular,Dystrophy, Macular,Macular Degeneration, Age Related,Macular Degenerations,Macular Dystrophies,Maculopathies,Maculopathy, Age Related
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010783 Photometry Measurement of the various properties of light. Photometries
D005260 Female Females
D005425 Flicker Fusion The point or frequency at which all flicker of an intermittent light stimulus disappears. Flicker Fusions,Fusion, Flicker,Fusions, Flicker
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D012168 Retinal Pigments Photosensitive protein complexes of varied light absorption properties which are expressed in the PHOTORECEPTOR CELLS. They are OPSINS conjugated with VITAMIN A-based chromophores. Chromophores capture photons of light, leading to the activation of opsins and a biochemical cascade that ultimately excites the photoreceptor cells. Retinal Photoreceptor Pigment,Retinal Pigment,Visual Pigment,Visual Pigments,Retinal Photoreceptor Pigments,Photoreceptor Pigment, Retinal,Photoreceptor Pigments, Retinal,Pigment, Retinal,Pigment, Retinal Photoreceptor,Pigment, Visual,Pigments, Retinal,Pigments, Retinal Photoreceptor,Pigments, Visual

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