Biomaterial Database

Plasmodium vivax cerebral malaria. 2007

Rajoo Thapa, and Vikram Patra, and Ritabrata Kundu

Department of Pediatrics, The Institute of Child Health, 11, Dr. Biresh Guha Street, Kolkata 700 017, India. rajoothapa@yahoo.co.in

We report two cases of Plasmodium vivax malaria (both aged 12 years) complicated by seizures and symptoms of diffuse meningoencephalitis. One had predominantly meningeal signs while in the other, purely encephalitis features were present. Both cases were treated with artesunate. Rarely, cerebral malaria is a presenting complication or occurs during the course of P. vivax infection.

UI	MeSH Term	Description	Entries
D008288	Malaria	A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.	Marsh Fever,Plasmodium Infections,Remittent Fever,Infections, Plasmodium,Paludism,Fever, Marsh,Fever, Remittent,Infection, Plasmodium,Plasmodium Infection
D008297	Male		Males
D010966	Plasmodium vivax	A protozoan parasite that causes vivax malaria (MALARIA, VIVAX). This species is found almost everywhere malaria is endemic and is the only one that has a range extending into the temperate regions.	Plasmodium vivaxs,vivax, Plasmodium
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000077332	Artesunate	A water-soluble, semi-synthetic derivative of the sesquiterpene lactone artemisinin with anti-malarial, anti-schistosomiasis, antiviral, and potential anti-neoplastic activities	Dihydroartemisinine-12-alpha-succinate,Malacef,Malartin,SM 804,SM-804,Sodium Artesunate,Succinyl Dihydroartemisinin,Dihydroartemisinin, Succinyl,Dihydroartemisinine 12 alpha succinate,SM804
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012717	Sesquiterpenes	Fifteen-carbon compounds formed from three isoprenoid units with general formula C15H24.	Farnesanes,Farnesene,Farnesenes,Sesquiterpene,Sesquiterpene Derivatives,Sesquiterpenoid,Sesquiterpenoids,Derivatives, Sesquiterpene
D016779	Malaria, Cerebral	A condition characterized by somnolence or coma in the presence of an acute infection with PLASMODIUM FALCIPARUM (and rarely other Plasmodium species). Initial clinical manifestations include HEADACHES; SEIZURES; and alterations of mentation followed by a rapid progression to COMA. Pathologic features include cerebral capillaries filled with parasitized erythrocytes and multiple small foci of cortical and subcortical necrosis. (From Adams et al., Principles of Neurology, 6th ed, p136)	Cerebral Malaria,Malaria Meningitis,Meningitis, Malaria
D020808	Central Nervous System Protozoal Infections	Infections of the brain, spinal cord, or meninges by single celled organisms of the former subkingdom known as protozoa. The central nervous system may be the primary or secondary site of protozoal infection. These diseases may occur as OPPORTUNISTIC INFECTIONS or arise in immunocompetent hosts.	CNS Protozoal Infections,Cerebral Protozoal Infections,Meningoencephalitis, Protozoal,Protozoal Infections, Central Nervous System,Acanthamoeba Meningoencephalitis,Amebic Meningoencephalitis,Balamuthia mandrillaris CNS Infection,Balamuthia mandrillaris Meningoencephalitis,Infection, Central Nervous System, Protozoal,Infections, Protozoal, Central Nervous System,Naegleria fowleri Infection,Naegleria fowleri Meningoencephalitis,Primary Amebic Meningoencephalitis,Protozoal Infections, Cerebral,Protozoal Meningoencephalitis,Sappinia diploidea Meningoencephalitis,Acanthamoeba Meningoencephalitides,Amebic Meningoencephalitides,Amebic Meningoencephalitides, Primary,Amebic Meningoencephalitis, Primary,Balamuthia mandrillaris Meningoencephalitides,CNS Protozoal Infection,Cerebral Protozoal Infection,Infection, CNS Protozoal,Infection, Cerebral Protozoal,Infection, Naegleria fowleri,Infections, CNS Protozoal,Meningoencephalitides, Acanthamoeba,Meningoencephalitides, Amebic,Meningoencephalitides, Balamuthia mandrillaris,Meningoencephalitides, Naegleria fowleri,Meningoencephalitides, Primary Amebic,Meningoencephalitides, Protozoal,Meningoencephalitides, Sappinia diploidea,Meningoencephalitis, Acanthamoeba,Meningoencephalitis, Amebic,Meningoencephalitis, Balamuthia mandrillaris,Meningoencephalitis, Naegleria fowleri,Meningoencephalitis, Primary Amebic,Meningoencephalitis, Sappinia diploidea,Naegleria fowleri Infections,Naegleria fowleri Meningoencephalitides,Primary Amebic Meningoencephalitides,Protozoal Infection, CNS,Protozoal Infection, Cerebral,Protozoal Infections, CNS,Protozoal Meningoencephalitides,Sappinia diploidea Meningoencephalitides