Biomaterial Database

Subfoveal fluid resolves slowly after pars plana vitrectomy for tractional retinal detachment secondary to proliferative diabetic retinopathy. 2007

Nazanin Barzideh, and T Mark Johnson

National Retina Institute, Chevy Chase, Maryland 20815, USA.

OBJECTIVE To report delayed visual recovery resulting from slow resolution of subfoveal subretinal fluid measured with optical coherence tomography (OCT) after pars plana vitrectomy (PPV) for repair of tractional retinal detachment (TRD) involving the fovea secondary to proliferative diabetic retinopathy (PDR). METHODS In this retrospective case series, charts of three patients with persistent subfoveal fluid after PPV for TRD secondary to PDR were reviewed. All patients were followed up for a minimum of 1 year after surgery, using OCT and serial ophthalmic examination. RESULTS Subfoveal fluid resolved completely after a minimum of 6 months after PPV as measured by OCT. All three patients had improvement in visual acuity after subfoveal fluid was completely resolved. CONCLUSIONS Persistent subfoveal fluid may take several months to resolve in patients undergoing PPV to repair TRD secondary to PDR and account for delayed visual recovery. OCT is an important tool in the follow-up of patients undergoing vitrectomy for TRD.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D012163	Retinal Detachment	Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).	Retinal Pigment Epithelial Detachment,Detachment, Retinal,Detachments, Retinal,Retinal Detachments
D001826	Body Fluids	Liquid components of living organisms.	Body Fluid,Fluid, Body,Fluids, Body
D003930	Diabetic Retinopathy	Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.	Diabetic Retinopathies,Retinopathies, Diabetic,Retinopathy, Diabetic
D005122	Exudates and Transudates	Exudates are fluids, CELLS, or other cellular substances that are slowly discharged from BLOOD VESSELS usually from inflamed tissues. Transudates are fluids that pass through a membrane or squeeze through tissue or into the EXTRACELLULAR SPACE of TISSUES. Transudates are thin and watery and contain few cells or PROTEINS.	Transudates,Exudates,Transudates and Exudates,Exudate,Transudate
D005260	Female		Females
D005451	Fluorescein Angiography	Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.	Fluorescence Angiography,Fundus Fluorescence Photography,Angiography, Fluorescein,Angiography, Fluorescence,Fluorescence Photography, Fundus,Photography, Fundus Fluorescence
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective