Analysis of benzophenones by gas chromatography/Fourier transform-infrared spectrometry. 1991

T Minagawa, and S Suzuki, and T Suzuki
Criminal Investigation Laboratories, Yamagata Police H.Q., Matsunami, Japan.

A gas chromatograph/Fourier transform-infrared spectrometric analysis of benzophenones, as hydrolyzed products of benzodiazepine, was evaluated and the vapor phase spectra obtained were compared with those measured in the condensed phase. Each infrared spectrum obtained in the vapor phase showed a much greater difference in comparison to differences found in those in the condensed phase, especially in the fingerprint region. The identification of 14 benzophenones by their infrared spectra in the vapor phase was possible. The detection limits for these benzophenones were between 50-100 ng with high signal-to-noise ratios. The vapor phase spectra of the benzophenones were unique and the analytical method allowed the differentiation of closely related classes of drugs, such as benzophenones.

UI MeSH Term Description Entries
D002849 Chromatography, Gas Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix. Chromatography, Gas-Liquid,Gas Chromatography,Chromatographies, Gas,Chromatographies, Gas-Liquid,Chromatography, Gas Liquid,Gas Chromatographies,Gas-Liquid Chromatographies,Gas-Liquid Chromatography
D006868 Hydrolysis The process of cleaving a chemical compound by the addition of a molecule of water.
D001569 Benzodiazepines A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring. Benzodiazepine,Benzodiazepine Compounds
D001577 Benzophenones Derivatives of benzophenone (with the structural formula phenyl-(C
D013055 Spectrophotometry, Infrared Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) IR Spectra,Infrared Spectrophotometry,IR Spectras,Spectra, IR
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular

Related Publications

T Minagawa, and S Suzuki, and T Suzuki
August 1989, Journal of chromatography,
T Minagawa, and S Suzuki, and T Suzuki
September 1999, Journal of chromatography. A,
T Minagawa, and S Suzuki, and T Suzuki
March 1994, Journal of chromatography. A,
T Minagawa, and S Suzuki, and T Suzuki
January 1987, The Journal of automatic chemistry,
Copied contents to your clipboard!