-transparent.png){kind=logo}
A physical map of the bovine genome. 2007
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
USDA, ARS, US Meat Animal Research Center, Clay Center, NE 68933, USA. warren.snelling@ars.usda.gov
BACKGROUND Cattle are important agriculturally and relevant as a model organism. Previously described genetic and radiation hybrid (RH) maps of the bovine genome have been used to identify genomic regions and genes affecting specific traits. Application of these maps to identify influential genetic polymorphisms will be enhanced by integration with each other and with bacterial artificial chromosome (BAC) libraries. The BAC libraries and clone maps are essential for the hybrid clone-by-clone/whole-genome shotgun sequencing approach taken by the bovine genome sequencing project. RESULTS A bovine BAC map was constructed with HindIII restriction digest fragments of 290,797 BAC clones from animals of three different breeds. Comparative mapping of 422,522 BAC end sequences assisted with BAC map ordering and assembly. Genotypes and pedigree from two genetic maps and marker scores from three whole-genome RH panels were consolidated on a 17,254-marker composite map. Sequence similarity allowed integrating the BAC and composite maps with the bovine draft assembly (Btau3.1), establishing a comprehensive resource describing the bovine genome. Agreement between the marker and BAC maps and the draft assembly is high, although discrepancies exist. The composite and BAC maps are more similar than either is to the draft assembly. CONCLUSIONS Further refinement of the maps and greater integration into the genome assembly process may contribute to a high quality assembly. The maps provide resources to associate phenotypic variation with underlying genomic variation, and are crucial resources for understanding the biology underpinning this important ruminant species so closely associated with humans.
Related Publications
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
January 1993,
Mammalian genome : official journal of the International Mammalian Genome Society,
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
December 2004,
Nature,
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
February 2001,
Nature,
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
August 2002,
Nature,
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
March 1994,
Nature genetics,
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
August 2009,
BMC genomics,
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
January 1997,
The Journal of eukaryotic microbiology,
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
March 1986,
Plant molecular biology,
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
April 1990,
Molecular microbiology,
Warren M Snelling, and
Readman Chiu, and
Jacqueline E Schein, and
Matthew Hobbs, and
Colette A Abbey, and
David L Adelson, and
Jan Aerts, and
Gary L Bennett, and
Ian E Bosdet, and
Mekki Boussaha, and
Rudiger Brauning, and
Alexandre R Caetano, and
Marcos M Costa, and
Allan M Crawford, and
Brian P Dalrymple, and
André Eggen, and
Annelie Everts-van der Wind, and
Sandrine Floriot, and
Mathieu Gautier, and
Clare A Gill, and
Ronnie D Green, and
Robert Holt, and
Oliver Jann, and
Steven Jm Jones, and
Steven M Kappes, and
John W Keele, and
Pieter J de Jong, and
Denis M Larkin, and
Harris A Lewin, and
John C McEwan, and
Stephanie McKay, and
Marco A Marra, and
Carrie A Mathewson, and
Lakshmi K Matukumalli, and
Stephen S Moore, and
Brenda Murdoch, and
Frank W Nicholas, and
Kazutoyo Osoegawa, and
Alice Roy, and
Hanni Salih, and
Laurent Schibler, and
Robert D Schnabel, and
Licia Silveri, and
Loren C Skow, and
Timothy Pl Smith, and
Tad S Sonstegard, and
Jeremy F Taylor, and
Ross Tellam, and
Curtis P Van Tassell, and
John L Williams, and
James E Womack, and
Natasja H Wye, and
George Yang, and
Shaying Zhao, and
April 2009,
BMC genetics,
