Particulate air pollution and mortality in the United States: did the risks change from 1987 to 2000? 2007

Francesca Dominici, and Roger D Peng, and Scott L Zeger, and Ronald H White, and Jonathan M Samet
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA. fdominic@jhsph.edu

Evaluation of the public health impact of air quality regulations, referred to as accountability research, is increasingly viewed as a necessary component of responsible governmental policy interventions. The authors present an example of accountability assessment based on evaluating change in the short-term effect of airborne particles over a period of increasingly stringent regulation that might have changed the chemical composition and toxicity of these particles. They used updated data and methods of the National Morbidity Mortality Air Pollution Study to estimate national average relative rates of the effects of particulate matter <or=10 microm in aerodynamic diameter on all-cause, cardiovascular, and respiratory mortality and on other-cause mortality for 1987-2000. They estimated national average relative rates of the effects of particulate matter <or=2.5 microm in aerodynamic diameter on all-cause mortality for 1999-2000. The authors found strong evidence that lag 1 exposures to particulate matter <or=10 microm and <or=2.5 microm in aerodynamic diameter continue to be associated with increased mortality. They also found a weak indication that the lag 1 effects of particulate matter <or=10 microm in aerodynamic diameter on mortality declined during 1987-2000 and that this decline occurred mostly in the eastern United States. The methodology presented can be used to track the health effects of air pollution routinely on regional and national scales.

UI MeSH Term Description Entries
D010316 Particle Size Relating to the size of solids. Particle Sizes,Size, Particle,Sizes, Particle
D011159 Population Surveillance Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy. Surveillance, Population
D011634 Public Health Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level. Community Health,Environment, Preventive Medicine & Public Health,Environment, Preventive Medicine and Public Health,Health, Community,Health, Public
D012140 Respiratory Tract Diseases Diseases involving the RESPIRATORY SYSTEM. Respiratory Diseases,Respiratory System Diseases,Disease, Respiratory System,Disease, Respiratory Tract,Respiratory System Disease,Respiratory Tract Disease
D002318 Cardiovascular Diseases Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. Adverse Cardiac Event,Cardiac Events,Major Adverse Cardiac Events,Adverse Cardiac Events,Cardiac Event,Cardiac Event, Adverse,Cardiac Events, Adverse,Cardiovascular Disease,Disease, Cardiovascular,Event, Cardiac
D004391 Dust Earth or other matter in fine, dry particles. (Random House Unabridged Dictionary, 2d ed) House Dust,Housedust,Dust, House
D004782 Environmental Health The science of controlling or modifying those conditions, influences, or forces surrounding man which relate to promoting, establishing, and maintaining health. Environmental Health Science,Health, Environmental,Environmental Health Sciences,Environmental Healths,Health Science, Environmental,Health Sciences, Environmental,Healths, Environmental,Science, Environmental Health,Sciences, Environmental Health
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000393 Air Pollutants Any substance in the air which could, if present in high enough concentration, harm humans, animals, vegetation or materials. Substances include GASES; PARTICULATE MATTER; and volatile ORGANIC CHEMICALS. Air Pollutant,Air Pollutants, Environmental,Environmental Air Pollutants,Environmental Pollutants, Air,Air Environmental Pollutants,Pollutant, Air,Pollutants, Air,Pollutants, Air Environmental,Pollutants, Environmental Air
D000397 Air Pollution The presence of contaminants or pollutant substances in the air (AIR POLLUTANTS) that interfere with human health or welfare, or produce other harmful environmental effects. The substances may include GASES; PARTICULATE MATTER; or volatile ORGANIC CHEMICALS. Air Quality,Air Pollutions,Pollution, Air

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