Biomaterial Database

[Excretion of trichloroacetic acid (TCA) in urine of workers exposed to trichloroethylene]. 1991

S Q Lü

Public Health School, Beijing Medical University.

The excretion pattern of TCA in urine of workers exposed to trichloroethylene and the correlation between concentration of TCA in urine and uptake amount of trichloroethylene were investigated by applying Head Space Gas Chromatography. We examined 33 unexposed subjects (control group) and 48 workers (exposure group). The results showed that the concentration of TCA in urine rose obviously after exposure to trichloroethylene. The concentration of TCA in urine and trichloroethylene exposure was positively correlated (X = 2.916Y + 4.619, r = 0.956 8). Based on the observation of 6 volunteers, we found that the concentration of TCA in urine reached its peak about 48 hours after exposure has ceased. It then slowly declined and did not recover completely up to 96 hours.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000395	Air Pollutants, Occupational	Toxic air-borne matter related to work performed They are usually produced by the specific nature of the occupation.	Occupational Air Pollutants,Pollutants, Occupational Air
D014238	Trichloroacetic Acid	A strong acid used as a protein precipitant in clinical chemistry and also as a caustic for removing warts.	Acide trichloracetique,Rubidium Trichloroacetate,Sodium Trichloroacetate,Acid, Trichloroacetic,Trichloroacetate, Rubidium,Trichloroacetate, Sodium,trichloracetique, Acide
D014241	Trichloroethylene	A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.	Ethinyl Trichloride,Trichloroethene,Trielina,Trilene,Trichloride, Ethinyl
D016273	Occupational Exposure	The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.	Exposure, Occupational,Exposures, Occupational,Occupational Exposures