[Endolymphatic therapy of children with chronic osteomyelitis of the long tubular bones]. 1991

S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk

A study was made of the clinical efficacy and immune status in 40 children with chronic osteomyelitis of long tubular bones. Of these, 13 patients received antibiotics endolymphatically and 27 patients were given conventional antibiotic therapy (intramuscularly, intravenously). In view of the predominance of the staphylococcal flora, endolymphatic therapy included the use of gentamycin and lincomycin, the treatment course lasted up to 10 days. Endolymphatic antibacterial therapy has been demonstrated to produce a beneficial clinical effect there was a decrease in fever duration, the amount of postoperative complications, and the duration of inpatient treatment. After endolymphatic therapy the patients' blood manifested a more remarkable, as compared to the control group, rise of the absolute count of T lymphocytes, "active" population of T lymphocytes, together with an increase of the functional activity of lymphocytes in blast transformation, and a reduction, to an equal degree, of the neutrophil and monocyte counts, attesting to a decline of antigenic load of phagocytes. In patients who received antibiotics endolymphatically, the general blood analysis showed a decrease of neutrophilia and marked lymphocytosis. All this mirrored the intensity of immunity activation.

UI MeSH Term Description Entries
D007113 Immunity, Innate The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS. Immunity, Native,Immunity, Natural,Immunity, Non-Specific,Resistance, Natural,Innate Immune Response,Innate Immunity,Immune Response, Innate,Immune Responses, Innate,Immunity, Non Specific,Innate Immune Responses,Native Immunity,Natural Immunity,Natural Resistance,Non-Specific Immunity
D007272 Injections, Intralymphatic Injections into the lymph nodes or the lymphatic system. Injections, Endolymphatic,Endolymphatic Injections,Intralymphatic Injections,Endolymphatic Injection,Injection, Endolymphatic,Injection, Intralymphatic,Intralymphatic Injection
D007866 Leg The inferior part of the lower extremity between the KNEE and the ANKLE. Legs
D008297 Male Males
D010019 Osteomyelitis INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA. Osteomyelitides
D011512 Proteus Infections Infections with bacteria of the genus PROTEUS. Infections, Proteus,Infection, Proteus,Proteus Infection
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002908 Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D004927 Escherichia coli Infections Infections with bacteria of the species ESCHERICHIA COLI. E coli Infections,E. coli Infection,Infections, E coli,Infections, Escherichia coli,E coli Infection,E. coli Infections,Escherichia coli Infection,Infection, E coli,Infection, E. coli,Infection, Escherichia coli
D005260 Female Females

Related Publications

S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
January 1955, Ortopediia travmatologiia i protezirovanie,
S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
August 1989, Khirurgiia,
S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
October 1987, Khirurgiia,
S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
December 1971, Ortopediia travmatologiia i protezirovanie,
S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
February 1980, Ortopediia travmatologiia i protezirovanie,
S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
January 1983, Klinicheskaia khirurgiia,
S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
April 1975, Khirurgiia,
S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
July 1984, Meditsinskaia radiologiia,
S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
January 1988, Sovetskaia meditsina,
S A Schastnyĭ, and S A Samsygin, and G A Kostomarova, and E V Varlamov, and V V Vlasenko, and E N Dolgina, and N D Ekk
November 1925, The Indian medical gazette,
Copied contents to your clipboard!