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The effect on the developing fetal testis of in utero exposure to 1-MHz, continuous-wave ultrasound in the spatial peak, temporal average intensity range 0.5-10 W/cm2 for durations of 400-30 sec on Day 9, 12, or 15 of gestation was determined. Results show that two subtle, yet potentially deleterious, effects occurred: a reduction in the Sertoli cell population and an apparent delay in the cessation of gonocyte mitosis. An increase was also seen in the number of fetal resorptions and stillborn pups per number of implantation sites in the exposed specimens as compared to the sham and cage controls. Because the reduction in testis weight was proportional to decreased body weight and because there was no difference in Sertoli cell numbers due to day of treatment, the testicular effects may reflect a generalized delay in growth. Whether this effect of ultrasound on fetal testis will be translated into an equal reduction in germ cell numbers in the adult testis remains to be determined.
K I Carnes, and
R A Hess, and
F Dunn
April 1997,
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire,
K I Carnes, and
R A Hess, and
F Dunn
January 2018,
Frontiers in pharmacology,
K I Carnes, and
R A Hess, and
F Dunn
November 2018,
Chemosphere,
K I Carnes, and
R A Hess, and
F Dunn
May 1996,
Journal of comparative pathology,
K I Carnes, and
R A Hess, and
F Dunn
December 2018,
Toxicology letters,
K I Carnes, and
R A Hess, and
F Dunn
March 2019,
Environmental pollution (Barking, Essex : 1987),
K I Carnes, and
R A Hess, and
F Dunn
August 2017,
Environmental science & technology,
K I Carnes, and
R A Hess, and
F Dunn
May 2013,
Endocrinology,
K I Carnes, and
R A Hess, and
F Dunn
October 2023,
Environmental science & technology,
K I Carnes, and
R A Hess, and
F Dunn
August 2000,
Anatomia, histologia, embryologia,
