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XC cells originally derived from the tumor of a rat previously inoculated with the Prague strain of Rous sarcoma virus were used to induce tumors in chickens surgically thymectomized or bursectomized in the newly hatched period. Thymectomized chickens had a significantly higher incidence of tumors, larger tumors, and a higher tumor mortality, compared with control chickens, when both groups were given 5 X 10(6) XC cells into the wing webs. Bursectomy could significantly influence the tumor size only. It appeared that the capacity of XC cells to induce tumors and the growth of such tumors were subject to immunological influence, with the thymus playing a major and the bursa of Fabricus a minor role under the conditions used.
K M Lam, and
T J Linna
January 1967,
Folia biologica,
K M Lam, and
T J Linna
January 1963,
International archives of allergy and applied immunology,
K M Lam, and
T J Linna
January 1991,
Archivum immunologiae et therapiae experimentalis,
K M Lam, and
T J Linna
August 1977,
Experientia,
K M Lam, and
T J Linna
October 1974,
Experientia,
K M Lam, and
T J Linna
September 1974,
Journal of immunology (Baltimore, Md. : 1950),
K M Lam, and
T J Linna
January 1971,
Acta veterinaria Academiae Scientiarum Hungaricae,
K M Lam, and
T J Linna
May 1970,
Sabouraudia,
K M Lam, and
T J Linna
February 1971,
The Journal of parasitology,
K M Lam, and
T J Linna
May 1969,
The American journal of tropical medicine and hygiene,
