Efficient, one-pot syntheses of biologically active alpha-linked glycolipids. 2007

Wenjun Du, and Suvarn S Kulkarni, and Jacquelyn Gervay-Hague
Department of Chemistry, University of California Davis, One Shields Avenue, Davis, CA 95616, USA.

Per-O-silylated galactosyl iodides undergo alpha-glycosidation with fully functionalized glycolipids producing biologically relevant conjugates.

UI MeSH Term Description Entries
D007694 Killer Cells, Natural Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type. NK Cells,Natural Killer Cells,Cell, NK,Cell, Natural Killer,Cells, NK,Cells, Natural Killer,Killer Cell, Natural,NK Cell,Natural Killer Cell
D006017 Glycolipids Any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic moiety such as an acylglycerol (see GLYCERIDES), a sphingoid, a ceramide (CERAMIDES) (N-acylsphingoid) or a prenyl phosphate. (From IUPAC's webpage) Glycolipid
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D055610 Antigens, CD1d A major histocompatibility complex class I-like protein that contains an IMMUNOGLOBULIN C1-SET DOMAIN. It plays a unique role in the presentation of lipid ANTIGENS to NATURAL KILLER T-CELLS. CD1d Antigen,Cd1d Molecule,Antigen, CD1d,CD1d Antigens
D018949 Antigens, CD1 Glycoproteins expressed on cortical thymocytes and on some dendritic cells and B-cells. Their structure is similar to that of MHC Class I and their function has been postulated as similar also. CD1 antigens are highly specific markers for human LANGERHANS CELLS. CD1 Antigens,CD1 Antigen,Antigen, CD1

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