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By means of the application of UV-inactivated Sendai virus interspecific hybrids of Dzungarian hamsterXmouse somatic cells were obtained in HAT selective medium. Karyotypic changes in these hybrid somatic cells were recorded during a 13 months' period. In the beginning each hybrid somatic cell contained 1 chromosome set of Dzungarian hamster and 1 mouse chromosome set. It was observed that throughout 13 months' of cultivation the elimination of Dzungarian hamster chromosomes prevailed over that of mouse chromosomes.
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