[Computer selection of thrombocyte donors based on the HLA system]. 1991

M Bláha, and P Stránský, and M Pecka, and J Malý
Vojenská lékarská akademie, Hradec Králové.

Thrombocyte concentrates are vitally important in thrombocytopenic types of haemorrhage. If repeated transfusions are necessary, they are associated with immunological reactions, which cause side-effects in the recipient and the transfusion is ineffective. Donors should be selected according to the HLA system. The authors prepared a programme in the Redap language for selection of donors according to HLA antigens (loci A and B) which respects cross reactions and split antigens. The donor is selected by the grade of agreement with the recipient. The authors differentiate between nine possibilities from complete agreement to complete disagreement between donor and recipient. The initial experience revealed that the programme is feasible for the user and is sufficiently quick.

UI MeSH Term Description Entries
D010983 Plateletpheresis The preparation of platelet concentrates with the return of red cells and platelet-poor plasma to the donor. Blood Plateletpheresis,Thrombocytapheresis,Thrombocytopheresis,Blood Plateletphereses,Plateletphereses,Plateletphereses, Blood,Plateletpheresis, Blood,Thrombocytaphereses,Thrombocytophereses
D012042 Registries The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers. Parish Registers,Population Register,Parish Register,Population Registers,Register, Parish,Register, Population,Registers, Parish,Registers, Population,Registry
D001782 Blood Donors Individuals supplying blood or blood components for transfer to histocompatible recipients. Blood Donor,Donor, Blood,Donors, Blood
D006648 Histocompatibility The degree of antigenic similarity between the tissues of different individuals, which determines the acceptance or rejection of allografts. HLA Incompatibility,Histoincompatibility,Human Leukocyte Antigen Incompatibility,Immunocompatibility,Tissue Compatibility,Compatibility, Tissue,HLA Incompatibilities,Histocompatibilities,Histoincompatibilities,Immunocompatibilities,Incompatibility, HLA,Tissue Compatibilities
D006680 HLA Antigens Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases. Human Leukocyte Antigen,Human Leukocyte Antigens,Leukocyte Antigens,HL-A Antigens,Antigen, Human Leukocyte,Antigens, HL-A,Antigens, HLA,Antigens, Human Leukocyte,Antigens, Leukocyte,HL A Antigens,Leukocyte Antigen, Human,Leukocyte Antigens, Human
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012984 Software Sequential operating programs and data which instruct the functioning of a digital computer. Computer Programs,Computer Software,Open Source Software,Software Engineering,Software Tools,Computer Applications Software,Computer Programs and Programming,Computer Software Applications,Application, Computer Software,Applications Software, Computer,Applications Softwares, Computer,Applications, Computer Software,Computer Applications Softwares,Computer Program,Computer Software Application,Engineering, Software,Open Source Softwares,Program, Computer,Programs, Computer,Software Application, Computer,Software Applications, Computer,Software Tool,Software, Computer,Software, Computer Applications,Software, Open Source,Softwares, Computer Applications,Softwares, Open Source,Source Software, Open,Source Softwares, Open,Tool, Software,Tools, Software

Related Publications

M Bláha, and P Stránský, and M Pecka, and J Malý
January 1984, Transfusion,
M Bláha, and P Stránský, and M Pecka, and J Malý
January 1990, Beitrage zur Infusionstherapie = Contributions to infusion therapy,
M Bláha, and P Stránský, and M Pecka, and J Malý
May 1984, Medicina clinica,
M Bláha, and P Stránský, and M Pecka, and J Malý
January 1985, Folia haematologica (Leipzig, Germany : 1928),
M Bláha, and P Stránský, and M Pecka, and J Malý
January 1988, Beitrage zur Infusionstherapie = Contributions to infusion therapy,
M Bláha, and P Stránský, and M Pecka, and J Malý
December 1997, Transplantation proceedings,
M Bláha, and P Stránský, and M Pecka, and J Malý
January 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation,
M Bláha, and P Stránský, and M Pecka, and J Malý
October 1996, Human immunology,
M Bláha, and P Stránský, and M Pecka, and J Malý
December 1996, Human immunology,
M Bláha, and P Stránský, and M Pecka, and J Malý
August 2012, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis,
Copied contents to your clipboard!