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Afterdischarges during cortical stimulation at different frequencies and intensities. 2007
Gholam K Motamedi, and
Oladotun Okunola, and
Christopher G Kalhorn, and
Navid Mostofi, and
Yuko Mizuno-Matsumoto, and
Yong-Won Cho, and
Kimford J Meador
Department of Neurology, PHC 7, Georgetown University Hospital, 3800 Reservior Rd., NW, Washington, DC 20007, USA. Motamedi@georgetown.edu
OBJECTIVE The occurrence of unwanted afterdischarges (ADs) impedes cortical stimulation for mapping purposes. We investigated the safety of several stimulation paradigms. METHODS We compared the incidence of ADs and behavioral responses of two stimulation frequencies (50 and 100 Hz), at two intensities (1 and 0.2 ms pulse widths). RESULTS Stimulation with 100 Hz was more likely to cause ADs than 50 Hz, and stimulation using 1 ms pulse width was more likely to cause ADs than 0.2 ms. CONCLUSIONS Stimulation using 50 Hz frequency with a pulse width of 0.2 ms might be safer during cortical mapping.
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