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A highly repetitive component in rat nuclear DNA was isolated by HindIII digestion and cloned. A 370-bp cloned component was highly AT-rich (68.3%) in about one third of the region from the 3'-terminus and showed an anomalously slow gel electrophoretic mobility (k-factor = 1.19). These results indicated that a sequence-directed bending of the helix axis occurs in the component. Accordingly, a subclone containing a tandem dimer of the component was isolated and subjected to a circular permutation analysis for exploring the bend center (1). In consequence, the center was shown to be present in the sequence ranging from position near 270 to the 3'-terminus and estimated to be located around position 340.
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
September 1979,
Nucleic acids research,
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
November 1998,
Biochemical and biophysical research communications,
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
March 1998,
Biochimica et biophysica acta,
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
April 1992,
Biochemical and biophysical research communications,
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
October 1989,
Biochemistry international,
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
January 1981,
Journal of molecular biology,
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
December 2000,
Biochemical and biophysical research communications,
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
January 1995,
Cancer letters,
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
August 1993,
Biochimica et biophysica acta,
K Nakamura, and
Y Ikeda, and
N Iwakami, and
Y Hibino, and
N Sugano
January 1993,
Receptor,
