[Confirmation of a positive genetic relationship between pendulum movements, audiogenic epilepsy, catalepsy, and "nervousness" in rats]. 2007

N N Barykina, and V F Chugu, and O I Prokudina, and I Z Pliusnina, and V G Kolpakov

Relationships between the predispositions to pendulum movements (PMs), catalepsy, and audiogenic epilepsy in the course of breeding for "nervousness" and freezing have been studied. A positive genetic relationship between PMs, catalepsy, and audiogenic epilepsy has been demonstrated. Eighty to ninety percent of rats selected for enhanced PMs (strain PM+) exhibit predisposition to audiogenic seizures, whereas this frequency in the PM-free strain (PM-) is 10-40%.

UI MeSH Term Description Entries
D008297 Male Males
D002375 Catalepsy A condition characterized by inactivity, decreased responsiveness to stimuli, and a tendency to maintain an immobile posture. The limbs tend to remain in whatever position they are placed (waxy flexibility). Catalepsy may be associated with PSYCHOTIC DISORDERS (e.g., SCHIZOPHRENIA, CATATONIC), nervous system drug toxicity, and other conditions. Cerea Flexibilitas,Flexibility, Waxy,Anochlesia,Anochlesias,Catalepsies,Flexibilitas, Cerea,Flexibilities, Waxy,Waxy Flexibilities,Waxy Flexibility
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001007 Anxiety Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS. Angst,Anxiousness,Hypervigilance,Nervousness,Social Anxiety,Anxieties, Social,Anxiety, Social,Social Anxieties
D012641 Selection, Genetic Differential and non-random reproduction of different genotypes, operating to alter the gene frequencies within a population. Natural Selection,Genetic Selection,Selection, Natural
D013239 Stereotyped Behavior Relatively invariant mode of behavior elicited or determined by a particular situation; may be verbal, postural, or expressive. Behavior, Stereotyped,Behaviors, Stereotyped,Stereotyped Behaviors
D017208 Rats, Wistar A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain. Wistar Rat,Rat, Wistar,Wistar Rats
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D020195 Epilepsy, Reflex A subtype of epilepsy characterized by seizures that are consistently provoked by a certain specific stimulus. Auditory, visual, and somatosensory stimuli as well as the acts of writing, reading, eating, and decision making are examples of events or activities that may induce seizure activity in affected individuals. (From Neurol Clin 1994 Feb;12(1):57-8) Reflex Epilepsy,Reflex Epilepsy, Audiogenic,Reflex Epilepsy, Cursive (Running),Reflex Epilepsy, Eating-Induced,Reflex Epilepsy, Musicogenic,Reflex Epilepsy, Photosensitive,Reflex Epilepsy, Reading,Audiogenic Epilepsy,Cursive Epilepsy,Decision Making Reflex Epilepsy,Eating-Induced Epilepsy,Epilepsy, Photogenic,Epilepsy, Reading,Immersion Related Epilepsy,Musicogenic Epilepsy,Photosensitive Epilepsy,Reading Epilepsy,Reflex Epilepsy, Visual Pattern,Tactile Reflex Epilepsy,Visual Pattern Reflex Epilepsy,Writing-Induced Reflex Epilepsy,Audiogenic Epilepsies,Audiogenic Reflex Epilepsies,Audiogenic Reflex Epilepsy,Cursive Reflex Epilepsies (Running),Cursive Reflex Epilepsy (Running),Eating Induced Epilepsy,Eating-Induced Epilepsies,Eating-Induced Reflex Epilepsies,Eating-Induced Reflex Epilepsy,Epilepsies, Audiogenic Reflex,Epilepsies, Cursive,Epilepsies, Eating-Induced,Epilepsies, Eating-Induced Reflex,Epilepsies, Immersion Related,Epilepsies, Musicogenic,Epilepsies, Musicogenic Reflex,Epilepsies, Photosensitive,Epilepsies, Photosensitive Reflex,Epilepsies, Reading,Epilepsies, Reading Reflex,Epilepsies, Reflex,Epilepsies, Tactile Reflex,Epilepsies, Writing-Induced Reflex,Epilepsy, Audiogenic,Epilepsy, Audiogenic Reflex,Epilepsy, Cursive,Epilepsy, Cursive Reflex (Running),Epilepsy, Eating-Induced,Epilepsy, Eating-Induced Reflex,Epilepsy, Immersion Related,Epilepsy, Musicogenic,Epilepsy, Musicogenic Reflex,Epilepsy, Photosensitive,Epilepsy, Photosensitive Reflex,Epilepsy, Reading Reflex,Epilepsy, Tactile Reflex,Epilepsy, Writing-Induced Reflex,Immersion Related Epilepsies,Musicogenic Epilepsies,Musicogenic Reflex Epilepsies,Musicogenic Reflex Epilepsy,Photosensitive Epilepsies,Photosensitive Reflex Epilepsies,Photosensitive Reflex Epilepsy,Reading Epilepsies,Reading Reflex Epilepsies,Reading Reflex Epilepsy,Reflex Epilepsies,Reflex Epilepsies, Audiogenic,Reflex Epilepsies, Cursive (Running),Reflex Epilepsies, Eating-Induced,Reflex Epilepsies, Musicogenic,Reflex Epilepsies, Photosensitive,Reflex Epilepsies, Reading,Reflex Epilepsies, Tactile,Reflex Epilepsies, Writing-Induced,Reflex Epilepsy, Eating Induced,Reflex Epilepsy, Tactile,Reflex Epilepsy, Writing-Induced,Tactile Reflex Epilepsies,Writing Induced Reflex Epilepsy,Writing-Induced Reflex Epilepsies

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