Biomaterial Database

V lambda genes in chronic lymphocytic leukaemia: highly skewed V gene segment usage with similar CDR3 sequences. 2008

A Abusedra, and R Joshi, and A Bybee, and J F Apperley, and S D Wagner

UI	MeSH Term	Description	Entries
D007146	Immunoglobulin lambda-Chains	One of the types of light chain subunits of the immunoglobulins with a molecular weight of approximately 22 kDa.	Ig lambda Chains,Immunoglobulins, lambda-Chain,Immunoglobulin lambda-Chain,lambda-1-Immunoglobulin,lambda-2-Immunoglobulin,lambda-Chain Immunoglobulins,lambda-Immunoglobulin Light Chain,lambda-Immunoglobulin Light Chains,lambda-x Immunoglobulin,Chains, Ig lambda,Chains, lambda-Immunoglobulin Light,Immunoglobulin lambda Chain,Immunoglobulin lambda Chains,Immunoglobulin, lambda-x,Immunoglobulins, lambda Chain,Light Chain, lambda-Immunoglobulin,Light Chains, lambda-Immunoglobulin,lambda 1 Immunoglobulin,lambda 2 Immunoglobulin,lambda Chain Immunoglobulins,lambda Chains, Ig,lambda Immunoglobulin Light Chain,lambda Immunoglobulin Light Chains,lambda x Immunoglobulin,lambda-Chain, Immunoglobulin,lambda-Chains, Immunoglobulin
D004252	DNA Mutational Analysis	Biochemical identification of mutational changes in a nucleotide sequence.	Mutational Analysis, DNA,Analysis, DNA Mutational,Analyses, DNA Mutational,DNA Mutational Analyses,Mutational Analyses, DNA
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001483	Base Sequence	The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.	DNA Sequence,Nucleotide Sequence,RNA Sequence,DNA Sequences,Base Sequences,Nucleotide Sequences,RNA Sequences,Sequence, Base,Sequence, DNA,Sequence, Nucleotide,Sequence, RNA,Sequences, Base,Sequences, DNA,Sequences, Nucleotide,Sequences, RNA
D015322	Gene Rearrangement, B-Lymphocyte	Ordered rearrangement of B-lymphocyte variable gene regions coding for the IMMUNOGLOBULIN CHAINS, thereby contributing to antibody diversity. It occurs during the differentiation of the IMMATURE B-LYMPHOCYTES.	B-Cell Gene Rearrangement,B-Lymphocyte Gene Rearrangement,Gene Rearrangement, B-Cell,B Cell Gene Rearrangement,B Lymphocyte Gene Rearrangement,B-Cell Gene Rearrangements,B-Lymphocyte Gene Rearrangements,Gene Rearrangement, B Cell,Gene Rearrangement, B Lymphocyte,Gene Rearrangements, B-Cell,Gene Rearrangements, B-Lymphocyte,Rearrangement, B-Cell Gene,Rearrangement, B-Lymphocyte Gene,Rearrangements, B-Cell Gene,Rearrangements, B-Lymphocyte Gene
D015448	Leukemia, B-Cell	A malignant disease of the B-LYMPHOCYTES in the bone marrow and/or blood.	B-Cell Leukemia,B-Lymphocytic Leukemia,Leukemia, Lymphocytic, B-Cell,Lymphocytic Leukemia, B-Cell,Leukemia, Lymphocytic, B Cell,B Cell Leukemia,B Lymphocytic Leukemia,B-Cell Leukemias,B-Cell Lymphocytic Leukemia,B-Cell Lymphocytic Leukemias,B-Lymphocytic Leukemias,Leukemia, B Cell,Leukemia, B-Cell Lymphocytic,Leukemia, B-Lymphocytic,Leukemias, B-Cell,Leukemias, B-Cell Lymphocytic,Leukemias, B-Lymphocytic,Lymphocytic Leukemia, B Cell,Lymphocytic Leukemias, B-Cell
D022801	Complementarity Determining Regions	Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).	Complementarity Determining Region,Complementarity Determining Region 1,Complementarity Determining Region 2,Complementarity Determining Region 3,Complementarity Determining Region I,Complementarity Determining Region II,Complementarity Determining Region III,Complementarity-Determining Region,Complementarity-Determining Region 3,Hypervariable Region, Immunoglobulin,Hypervariable Regions, Immunoglobulin,Third Complementarity-Determining Region,Complementarity-Determining Region 3s,Complementarity-Determining Region, Third,Complementarity-Determining Regions,Complementarity-Determining Regions, Third,Immunoglobulin Hypervariable Region,Immunoglobulin Hypervariable Regions,Region, Complementarity Determining,Region, Immunoglobulin Hypervariable,Regions, Complementarity Determining,Regions, Complementarity-Determining,Regions, Immunoglobulin Hypervariable,Third Complementarity Determining Region,Third Complementarity-Determining Regions