[Anti-gliadin antibodies in the diagnosis and follow-up of celiac disease]. 1991

P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
II Clinica Pediatrica G. Gaslin, Università degli Studi di Genova.

The study assessed the value of anti-gliadin antibodies (AGA) as a diagnostic test for celiac disease (CD) by examining 219 children: 57 were affected by malabsorption syndrome and underwent the first duodenojejunal biopsy; 83 underwent a secondary diagnostic phase for CD; 44 underwent a challenge test; 35 controls. Duodenojejunal biopsy was performed in all subjects in the three stages of diagnosis for CD. By comparing AGA levels and on the basis of histological tests of duodenojejunal mucosa it is possible to confirm the reliability of the method as a screening test for use in subjects whose clinical symptoms suggest CD. AGA are however less reliable in the second and third stages, that is to say in the follow-up of CD, since they do not always reflect the conditions of intestinal mucosa.

UI MeSH Term Description Entries
D007583 Jejunum The middle portion of the SMALL INTESTINE, between DUODENUM and ILEUM. It represents about 2/5 of the remaining portion of the small intestine below duodenum. Jejunums
D002446 Celiac Disease A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION. Gluten Enteropathy,Sprue, Celiac,Sprue, Nontropical,Celiac Sprue,Gluten-Sensitive Enteropathy,Sprue,Disease, Celiac,Enteropathies, Gluten,Enteropathies, Gluten-Sensitive,Enteropathy, Gluten,Enteropathy, Gluten-Sensitive,Gluten Enteropathies,Gluten Sensitive Enteropathy,Gluten-Sensitive Enteropathies,Nontropical Sprue
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D004386 Duodenum The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers. Duodenums
D005903 Gliadin Simple protein, one of the prolamines, derived from the gluten of wheat, rye, etc. May be separated into 4 discrete electrophoretic fractions. It is the toxic factor associated with CELIAC DISEASE. alpha-Gliadin,alpha Gliadin
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000906 Antibodies Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
D001706 Biopsy Removal and pathologic examination of specimens from the living body. Biopsies

Related Publications

P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
June 2008, Digestive diseases and sciences,
P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
January 2009, Clinical chemistry,
P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
January 2015, PloS one,
P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
December 2012, Clinics and research in hepatology and gastroenterology,
P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
January 1987, Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg,
P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
January 1999, Medicina,
P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
January 1984, Indian journal of pediatrics,
P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
May 1991, Clinical chemistry,
P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
May 1990, Journal of pediatric gastroenterology and nutrition,
P Sbolgi, and G Mangiante, and G Ruffa, and F Caprioli, and G Bartolozzi, and M Cingolani, and G Gemme
February 2001, Pathologie-biologie,
Copied contents to your clipboard!