BIOMAT Database Logo BIOMAT Database Logo

Serum amyloid P and fibrosis in systemic sclerosis: comment on the article by Tennent et al. 2007

Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer

UI MeSH Term Description Entries
D008810 Mice, Inbred C57BL One of the first INBRED MOUSE STRAINS to be sequenced. This strain is commonly used as genetic background for transgenic mouse models. Refractory to many tumors, this strain is also preferred model for studying role of genetic variations in development of diseases. Mice, C57BL,Mouse, C57BL,Mouse, Inbred C57BL,C57BL Mice,C57BL Mice, Inbred,C57BL Mouse,C57BL Mouse, Inbred,Inbred C57BL Mice,Inbred C57BL Mouse
D005355 Fibrosis Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. Cirrhosis,Fibroses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000683 Serum Amyloid P-Component Amyloid P component is a small, non-fibrillar glycoprotein found in normal serum and in all amyloid deposits. It has a pentagonal (pentaxin) structure. It is an acute phase protein, modulates immunologic responses, inhibits ELASTASE, and has been suggested as an indicator of LIVER DISEASE. Amyloid P Component,Amyloid P-Component, Serum,P Component, Amyloid,P-Component, Serum Amyloid,Serum Amyloid P Component
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012595 Scleroderma, Systemic A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. Sclerosis, Systemic,Systemic Scleroderma,Systemic Sclerosis
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus
D018345 Mice, Knockout Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes. Knockout Mice,Mice, Knock-out,Mouse, Knockout,Knock-out Mice,Knockout Mouse,Mice, Knock out
D018450 Disease Progression The worsening and general progression of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis. Clinical Course,Clinical Progression,Disease Exacerbation,Exacerbation, Disease,Progression, Clinical,Progression, Disease

Related Publications

Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Microchimerism in systemic sclerosis: comment on the article by Johnson et al.
September 2002, Arthritis and rheumatism,
Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Systemic sclerosis sine scleroderma: comment on the article by Poormoghim et al.
November 2000, Arthritis and rheumatism,
Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Epitope spreading and systemic sclerosis: comment on the article by Kotani et al.
November 2025, Arthritis & rheumatology (Hoboken, N.J.),
Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Comment on the article "Hypocomplementemia in systemic sclerosis" by Cuomo G. et al.
January 2009, Reumatismo,
Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Dipeptidylpeptidase 4 as a Marker of Fibrosis in Systemic Sclerosis: Comment on the Article by Soare et al.
January 2021, Arthritis & rheumatology (Hoboken, N.J.),
Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Nephrogenic systemic fibrosis in patients undergoing hemodialysis: comment on the article by Todd et al.
March 2008, Arthritis and rheumatism,
Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Sexual function in women with systemic sclerosis: Comment on the article by Schouffoer et al.
August 2010, Arthritis care & research,
Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Mesenchymal Stem Cell Transplantation in Systemic Sclerosis: Comment on the Article by Maria et al.
September 2016, Arthritis & rheumatology (Hoboken, N.J.),
Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Patient-reported outcome measures in systemic sclerosis: comment on the article by Hinchcliff et al.
June 2012, Arthritis care & research,
Darrell Pilling, and Christopher D Buckley, and Mike Salmon, and Richard H Gomer
Extracellular vesicle pathogenic cues in systemic sclerosis: comment on the article by Mouawad et al.
January 2024, Arthritis & rheumatology (Hoboken, N.J.),
Copied contents to your clipboard!