Biomaterial Database

[Determination of pressure gradient across patent ductus arteriosus with simultaneous continuous wave Doppler and catheterization methods and non-invasive estimation of pulmonary artery pressure]. 1991

C Z Lu, and Y Y Hu, and Q L Xu

Affiliated Hospital, Shandong Medical University, Jinan.

To evaluate the accuracy of Doppler technique for measuring the pressure gradient (delta P) across patent ductus arteriosus (PDA) with a simplified Bernoulli equation (delta P = 4 V2) and estimating the pulmonary artery pressure (PAP) by subtracting delta P from brachial arterial pressure (BAP) measured with cuff sphygmomanometry, Doppler echocardiography and catheterization (both left and right) were performed simultaneously in 20 patients with PDA. For the values of systolic peak delta P (SPPG), mean delta P (MPG) and end-diastolic delta P (EDPG) determined by both Doppler and catheter, the correlation was excellent (r = 0.99, 0.99, 0.99). Doppler determined SPPG also correlated well with catheter determined peak to peak delta P (P-PPG) (r = 0.97). Comparison between Doppler-derived and catheter measured systolic PAP (SPAP), mean PAP (MPAP) and diastolic PAP (DPAP) also showed high correlation (r = 0.95, 0.98, 0.97). This study demonstrates that Doppler echocardiography is valuable for measurement of delta P across PDA and non-invasive estimation of PAP in patients with PDA.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D011651	Pulmonary Artery	The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.	Arteries, Pulmonary,Artery, Pulmonary,Pulmonary Arteries
D001794	Blood Pressure	PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.	Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D001795	Blood Pressure Determination	Techniques used for measuring BLOOD PRESSURE.	Blood Pressure Determinations,Determination, Blood Pressure
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D004374	Ductus Arteriosus, Patent	A congenital heart defect characterized by the persistent opening of fetal DUCTUS ARTERIOSUS that connects the PULMONARY ARTERY to the descending aorta (AORTA, DESCENDING) allowing unoxygenated blood to bypass the lung and flow to the PLACENTA. Normally, the ductus is closed shortly after birth.	Patent Ductus Arteriosus Familial,Patency of the Ductus Arteriosus,Patent Ductus Arteriosus
D005260	Female		Females
D006328	Cardiac Catheterization	Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.	Catheterization, Cardiac,Catheterization, Heart,Heart Catheterization,Cardiac Catheterizations,Catheterizations, Cardiac,Catheterizations, Heart,Heart Catheterizations
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths