Naturally-occurring Sendai virus infection of athymic nude mice. 1976

J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan

Nude (nu/nu) mice, Balb/c-derived, responded to a naturally-occurring Sendai virus infection in a different manner than conventional mice. They developed a chronic debilitating disease and a persistent viral infection of the respiratory tract with intranuclear inclusion bodies in tracheal, bronchial and bronchiolar epithelial cells, laryngeal and tracheal glandular epithelium and in type I and II alveolar cells. The infection was identified by serologic and tissue culture studies, the mouse antibody production test and ultrastructural examination of pulmonary lesions. Phlebitis of pulmonary veins, suppurative rhinitis and otitis media accompanied the viral infection while some mice developed a secondary bronchopneumonia.

UI MeSH Term Description Entries
D008168 Lung Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood. Lungs
D008819 Mice, Nude Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses. Athymic Mice,Mice, Athymic,Nude Mice,Mouse, Athymic,Mouse, Nude,Athymic Mouse,Nude Mouse
D010222 Parainfluenza Virus 1, Human A species of RESPIROVIRUS also called hemadsorption virus 2 (HA2), which causes laryngotracheitis in humans, especially children. Hemadsorption Virus 2,Human parainfluenza virus 1,Para-Influenza Virus Type 1,Parainfluenza Virus Type 1,Para Influenza Virus Type 1
D012141 Respiratory Tract Infections Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases. Respiratory System Infections,Upper Respiratory Tract Infection,Upper Respiratory Tract Infections,Infections, Respiratory,Infections, Respiratory Tract,Infections, Upper Respiratory,Infections, Upper Respiratory Tract,Respiratory Infections,Upper Respiratory Infections,Infection, Respiratory System,Infection, Respiratory Tract,Respiratory Infection, Upper,Respiratory System Infection,Respiratory Tract Infection
D001980 Bronchi The larger air passages of the lungs arising from the terminal bifurcation of the TRACHEA. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into BRONCHIOLES and PULMONARY ALVEOLI. Primary Bronchi,Primary Bronchus,Secondary Bronchi,Secondary Bronchus,Tertiary Bronchi,Tertiary Bronchus,Bronchi, Primary,Bronchi, Secondary,Bronchi, Tertiary,Bronchus,Bronchus, Primary,Bronchus, Secondary,Bronchus, Tertiary
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012376 Rodent Diseases Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs). Disease, Rodent,Diseases, Rodent,Rodent Disease
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus
D018184 Paramyxoviridae Infections Infections with viruses of the family PARAMYXOVIRIDAE. This includes MORBILLIVIRUS INFECTIONS; RESPIROVIRUS INFECTIONS; PNEUMOVIRUS INFECTIONS; HENIPAVIRUS INFECTIONS; AVULAVIRUS INFECTIONS; and RUBULAVIRUS INFECTIONS. Parainfluenza,Parainfluenza Virus Infections,Infections, Paramyxoviridae,Infection, Parainfluenza Virus,Infection, Paramyxoviridae,Infections, Parainfluenza Virus,Parainfluenza Virus Infection,Paramyxoviridae Infection,Virus Infection, Parainfluenza,Virus Infections, Parainfluenza

Related Publications

J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
April 1979, The Japanese journal of experimental medicine,
J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
December 1974, Laboratory animal science,
J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
June 1974, Nature,
J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
June 1977, Laboratory animal science,
J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
September 1979, Journal of immunology (Baltimore, Md. : 1950),
J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
December 1976, Laboratory animal science,
J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
January 1984, The Journal of pathology,
J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
February 1976, Journal of the Reticuloendothelial Society,
J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
March 1984, Infection and immunity,
J M Ward, and D P Houchens, and M J Collins, and D M Young, and R L Reagan
June 1978, Infection and immunity,
Copied contents to your clipboard!